Chung Sungjin, Park Cheol Whee, Chang Yoon Sik
St. Mary's Hospital, The Catholic University of Korea, Division of Nephrology, 62 Yeouido-dong, Yeongdeungpo-gu, Seoul, 150-713, Republic of Korea.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2009.1930. Epub 2009 Sep 9.
A percutaneous renal biopsy is the diagnostic procedure of choice in a variety of renal diseases. Although the risk is generally minimal, serious complications can rarely occur. Here we present the case of a 50-year-old male with renal amyloidosis due to myeloma, who suddenly developed left flank pain after a percutaneous renal biopsy. Imaging studies revealed a renal infarction with an intraluminal thrombus in the left wall of the descending aorta. Subsequent arterial thromboembolic events in the left limb followed immediately after the femoral arteriography. Arterial thromboembolism is a relatively rare, serious, unexpected and multifactorial event that occurs during an exacerbation of the nephrotic syndrome. In this case, the arterial vascular trauma from the renal biopsy and arterial puncture for angiography might have increased the risk for the thrombotic episode that resulted in death. Therefore, a thorough assessment for the risk factors prior to an invasive procedure such as a renal biopsy should be required so that patients at high risk can be identified.
经皮肾活检是多种肾脏疾病的首选诊断方法。虽然风险通常极小,但严重并发症仍可能罕见发生。在此,我们报告一例50岁男性骨髓瘤相关性肾淀粉样变性患者,其在经皮肾活检后突然出现左侧腰痛。影像学检查显示左肾梗死,降主动脉左壁腔内有血栓形成。随后,在股动脉造影后,左下肢立即发生动脉血栓栓塞事件。动脉血栓栓塞是肾病综合征加重期发生的一种相对罕见、严重、意外且多因素导致的事件。在本病例中,肾活检和血管造影动脉穿刺造成的动脉血管创伤可能增加了导致死亡的血栓形成事件的风险。因此,在进行诸如肾活检等侵入性操作前,应全面评估风险因素,以便识别高危患者。