Vaid Nidhi, Patel Parind
Chelsea and Westminster Hospital, London, UK.
Acute Med. 2011;10(3):142-4.
Disseminated histoplasmosis is an opportunistic infection which is commonly associated with HIV. Haemophagocytic lymphohistiocytosis (HLH) has been described as a secondary phenomenon to infection, collagen-vascular disorders and malignancies. In patients with HIV, cases of reactive haemophagocytic syndrome associated with disseminated histoplasmosis have been reported with CD4 counts of less than 50 cells/µl (450-1660 cells/µl). We report a case of a 25 year old man with HIV who presented with a CD4 count of 153 cells/µl and would suggest that this diagnosis should be considered at higher CD4 counts than previously reported.
播散性组织胞浆菌病是一种常见于艾滋病病毒感染者的机会性感染。噬血细胞性淋巴组织细胞增生症（HLH）被描述为感染、胶原血管疾病和恶性肿瘤的一种继发现象。在艾滋病病毒感染者中，已有报告称，CD4细胞计数低于50个/微升（450 - 1660个/微升）的患者出现了与播散性组织胞浆菌病相关的反应性噬血细胞综合征。我们报告了一例25岁的艾滋病病毒感染男性患者，其CD4细胞计数为153个/微升，并认为在高于先前报告的CD4细胞计数时就应考虑这一诊断。
