Departamento de Química, Universidade Federal de Santa Catarina, Florianópolis, SC 88040-970, Brazil.
Dalton Trans. 2011 Nov 21;40(43):11347-55. doi: 10.1039/c1dt11022e. Epub 2011 Sep 8.
In recent years, there has been an increasing application of chiral selenium compounds as ligands in metal-catalyzed enantioselective transformations. One of the most important challenges in this field is the development of new chiral complexes (catalyst) generated from the reaction between a metal and appropriate chiral selenium-containing compounds (ligand). The vast majority of these ligands are easily synthesized in a few high-yielding synthetic steps, starting from readily available chiral amino alcohols. In this context, the advantages of using these compounds will be discussed, mainly with regard to their easy accessibility, modular nature and the formation of strong bonds with soft or, more rarely, hard metals. Important selective contributions within the field of chiral selenium complexes are examined, according to their applications. As final remarks, future developments and perspectives of the field are discussed.
近年来，手性硒化合物作为配体在金属催化的对映选择性转化中得到了越来越多的应用。该领域的一个最重要的挑战是开发新的手性配合物（催化剂），这些配合物是由金属与适当的含手性硒的化合物（配体）之间的反应生成的。这些配体中的绝大多数都可以很容易地通过几种高产率的合成步骤，从容易获得的手性氨基醇开始合成。在这种情况下，将讨论使用这些化合物的优点，主要是因为它们易于获得、具有模块性以及与软金属或更罕见的硬金属形成强键。根据其应用，对手性硒配合物领域的重要选择性贡献进行了考察。最后，讨论了该领域的未来发展和前景。
