Department of Psychology, Fo Guang University, Taiwan.
J Clin Psychol. 2011 Oct;67(10):1080-91. doi: 10.1002/jclp.20833. Epub 2011 Aug 26.
We examined effects of stress, depression, and their interaction on sympathetic-parasympathetic responses, including percentage heart rate (PHR), percentage skin conductance (PSC), percentage finger temperature (PTEMP), and percentage respiratory rate (PRESPR). Participants were categorized into normal, low-risk, and high-risk depression groups under stress or no-stress by measuring psychophysiological responses. Stress increased PHR and PSC and decreased PTEMP. Depression negatively correlated with PHR and PTEMP. PSC and PTEMP were significantly dependent on and positively correlated with depression. PTEMP was significantly affected by the stress and depression interaction. Stress affects sympathetic, rather than parasympathetic, activity. Depression and the interaction between stress and depression initially associated with the sympathetic division and are then correlated with parasympathetic activity. A sympathetic-parasympathetic hypothesis and its clinical implications are discussed.
我们考察了压力、抑郁及其相互作用对交感神经-副交感神经反应的影响，包括心率百分比（PHR）、皮肤电导百分比（PSC）、手指温度百分比（PTEMP）和呼吸频率百分比（PRESPR）。通过测量生理心理反应，我们将参与者分为正常、低风险和高风险抑郁组，分别处于压力或无压力状态下。压力增加 PHR 和 PSC，降低 PTEMP。抑郁与 PHR 和 PTEMP 呈负相关。PSC 和 PTEMP 显著依赖于抑郁，并与抑郁呈正相关。PTEMP 受到压力和抑郁相互作用的显著影响。压力影响交感神经，而非副交感神经活动。抑郁和压力与抑郁的相互作用最初与交感神经有关，然后与副交感神经活动相关。讨论了交感神经-副交感神经假说及其临床意义。
