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关节内注射类固醇。风险效益评估。

Intra-articular steroid injection. A risk-benefit assessment.

作者信息

Grillet B, Dequeker J

机构信息

Department of Internal Medicine, Katholieke Universiteit Leuven, Belgium.

出版信息

Drug Saf. 1990 May-Jun;5(3):205-11. doi: 10.2165/00002018-199005030-00005.

Abstract

Intra-articular injections with steroids may offer additional help in the treatment of inflammatory joint diseases. The major side effects are the systemic effects of steroids, infectious arthritis and cartilage damage. These are infrequent, however, and to a great extent preventable. Steroids are of little effect in radiological progression and function, and this is the most important limitation on liberal use. On the other hand, they powerfully suppress inflammation and pain, for a varying length of time which depends on the preparation used.

摘要

关节内注射类固醇可能有助于治疗炎性关节疾病。主要副作用是类固醇的全身效应、感染性关节炎和软骨损伤。然而,这些副作用并不常见,而且在很大程度上是可以预防的。类固醇对放射学进展和功能影响不大,这是限制其广泛使用的最重要因素。另一方面,它们能在不同时长内有效抑制炎症和疼痛,时长取决于所使用的制剂。

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