Heelan Kara, Murphy Annette, Murphy Lesley-Ann
Department of Dermatology, Galway University Hospital, Galway, Ireland.
Pediatr Dermatol. 2012 Sep-Oct;29(5):618-20. doi: 10.1111/j.1525-1470.2011.01522.x. Epub 2011 Sep 9.
Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus results in leukocyte destruction and tissue necrosis (Pediatric Dermatology 2007;24:401). It can be associated with a spectrum of clinical manifestations that range from localized staphylococcal skin infections to sometimes severe necrotizing pneumonia (Clin Infect Dis 1999;29:1128). We report a case of four siblings, three brothers whose atopic dermatitis was complicated by cutaneous lesions and furunculosis, while their 21-month-old sister had a fatal PVL positive staphylococcal pneumonia.
产杀白细胞素（PVL）的金黄色葡萄球菌可导致白细胞破坏和组织坏死（《儿科皮肤病学》2007年；24卷：401页）。它可伴有一系列临床表现，从局部葡萄球菌皮肤感染到有时严重的坏死性肺炎（《临床传染病杂志》1999年；29卷：1128页）。我们报告一例四兄弟姐妹的病例，三个兄弟的特应性皮炎并发皮肤损害和疖病，而他们21个月大的妹妹患致命性PVL阳性葡萄球菌肺炎。
