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川崎病与斑秃:巧合还是真有关联?

Kawasaki disease and alopecia areata: coincidence or a true association?

作者信息

Krishnamurthy Sriram, Chandrashekar Laxmisha, Mondal Nivedita

机构信息

Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.

出版信息

Pediatr Dermatol. 2012 Jul-Aug;29(4):532-4. doi: 10.1111/j.1525-1470.2011.01527.x. Epub 2011 Sep 9.

DOI:10.1111/j.1525-1470.2011.01527.x
PMID:21906152
Abstract

A 10-year-old boy presented with fever, stiff neck, and rash over the legs. During the course of his hospital stay, the clinical picture gradually evolved, and he met the criteria for Kawasaki disease (KD) on the seventh day of hospitalization. During this period, he also developed alopecia areata. He was managed with intravenous immunoglobulin, aspirin, and intralesional triamcinolone. This is the first case of alopecia areata with KD in the literature, and it does not appear to be a mere coincidence. We discuss the probable mechanisms of alopecia areata with KD, an association that has not been reported before.

摘要

一名10岁男孩出现发热、颈部僵硬及腿部皮疹。在住院期间,临床表现逐渐演变,住院第7天符合川崎病(KD)标准。在此期间,他还患上了斑秃。给予静脉注射免疫球蛋白、阿司匹林及皮损内注射曲安奈德治疗。这是文献中首例KD合并斑秃的病例,似乎并非巧合。我们讨论了KD合并斑秃的可能机制,此前尚未有这种关联的报道。

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