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静脉注射甲泼尼龙治疗免疫球蛋白耐药型川崎病即将发生的心脏压塞。

Pulse methylprednisolone therapy for impending cardiac tamponade in immunoglobulin-resistant Kawasaki disease.

作者信息

Dahlem P G, von Rosenstiel I A, Lam J, Kuijpers T W

机构信息

Division of Pediatric Intensive Care, Department of Pediatrics, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.

出版信息

Intensive Care Med. 1999 Oct;25(10):1137-9. doi: 10.1007/s001340051025.

DOI:10.1007/s001340051025
PMID:10551972
Abstract

We describe a boy with Kawasaki disease (KD) whose clinical course was marked by a rapid improvement upon treatment with intravenous immunoglobulin (IVIG) and oral aspirin, which - within 14 days - was followed by the development of a large pericardial effusion with symptoms of impending cardiac tamponade as part of a polyserositis syndrome (pleural effusions, ascites). Upon treatment with pulsed methylprednisolone, the pericardial and pleural effusions and ascites rapidly disappeared within 48 h. This is the first case reported with a polyserositis syndrome and impending cardiac tamponade during KD.

摘要

我们描述了一名患有川崎病(KD)的男孩,其临床病程的特点是在接受静脉注射免疫球蛋白(IVIG)和口服阿司匹林治疗后迅速好转,但在14天内,又出现了大量心包积液,并伴有心脏压塞的症状,这是多浆膜炎综合征(胸腔积液、腹水)的一部分。在接受脉冲式甲泼尼龙治疗后,心包和胸腔积液以及腹水在48小时内迅速消失。这是首例报道的川崎病期间出现多浆膜炎综合征和即将发生心脏压塞的病例。

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Cardiovascular Involvement in Kawasaki Disease Is Much More Than Mere Coronary Arteritis.
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