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中国汉族男性血清铁蛋白参考值:一项中国男性人群调查的结果。

Reference values for serum ferritin in Chinese Han ethnic males: results from a Chinese male population survey.

机构信息

Department of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.

出版信息

Clin Biochem. 2011 Nov;44(16):1325-8. doi: 10.1016/j.clinbiochem.2011.08.1137. Epub 2011 Aug 31.

DOI:10.1016/j.clinbiochem.2011.08.1137
PMID:21907192
Abstract

OBJECTIVES

We calculated central-95-interpercentile reference values for serum ferritin (SF).

DESIGN AND METHODS

Serum samples were collected from the Fangchenggang Area Male Health and Examination Survey (FAMHES). After screening, we enrolled a total of 1,223 Chinese Han men between the ages of 20 and 69 years. SF values were measured by electrochemiluminescence immunoassay. The two-sided 95-percentile reference values were calculated using both parametric and nonparametric statistical methods.

RESULTS

SF values were distributed log-normally. The central-95-percentile reference values for SF were 88.2-771.7 μg/L (nonparametric) or 104.0-832.2 μg/L (parametric). Neither the non-smoking and smoking group (P=0.921) nor the non-drinking and drinking group (P=0.584) exhibited any difference in SF. Higher concentrations of SF were associated with a higher Body Mass Index (BMI) (r=0.266, P<10(-5)) but not with increasing age of the participants (P=0.808).

CONCLUSION

The reference values for SF calculated in this study are higher than previously-reported reference levels.

摘要

目的

我们计算了血清铁蛋白(SF)的 95%中心百分位参考值。

设计和方法

从防城港男性健康与体检调查(FAMHES)中采集血清样本。经过筛选,我们共招募了 1223 名年龄在 20 至 69 岁之间的汉族男性。SF 值通过电化学发光免疫分析法测定。使用参数和非参数统计方法计算双侧 95%百分位参考值。

结果

SF 值呈对数正态分布。SF 的 95%中心百分位参考值为 88.2-771.7μg/L(非参数)或 104.0-832.2μg/L(参数)。非吸烟组和吸烟组(P=0.921)以及非饮酒组和饮酒组(P=0.584)之间的 SF 值没有差异。SF 的浓度越高,体重指数(BMI)越高(r=0.266,P<10(-5)),但与参与者的年龄增加无关(P=0.808)。

结论

本研究计算的 SF 参考值高于以前报告的参考水平。

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