Department of the Cardiovascular Surgery, Kitasato University School of Medicine, Kanagawa, Japan.
J Thorac Cardiovasc Surg. 2012 Jul;144(1):130-8. doi: 10.1016/j.jtcvs.2011.08.013. Epub 2011 Sep 9.
The study objective was to evaluate various types of Norwood arch reconstruction methods and to show the factors that affect the cardiac workload of the single ventricle. The Norwood procedure is one of the most challenging congenital heart surgeries. Several aortic arch reconstruction techniques have been reported to avoid recoarctation, ensure coronary perfusion, and improve long-term outcomes. Inside the arch, complicated turbulent flow is generated; however, little is known about the cause of the disadvantageous inefficient flow and the surgical techniques to avoid it.
We created patient-specific computational hemodynamic models of 9 patients who underwent different types of arch reconstruction methods. Four patients had aortic atresia, and 5 patients had aortic stenosis. Flow profiles were defined by echocardiography data corrected with body surface area. Turbulent pulsatile flow was analyzed with the finite volume method. Flow energy loss was calculated to estimate cardiac workload, and wall shear stress was calculated to estimate vessel wall stiffness increase.
Recoarctation and acute arch angles increased wall shear stress and energy loss. In the patients with aortic atresia, a longitudinal incision toward the descending aorta was effective in creating a smooth arch angle. In the patients with aortic stenosis, arch repair with the Damus-Kaye-Stansel procedure in a single anastomotic site was effective in creating sufficient anastomosis space and a smooth arch angle.
Creation of a large anastomotic space and a smooth aortic arch angle reduced wall shear stress and energy loss, and should improve long-term cardiac performance after the Norwood procedure.
本研究旨在评估各种类型的 Norwood 弓重建方法,并展示影响单心室心脏工作量的因素。Norwood 手术是最具挑战性的先天性心脏手术之一。已经报道了几种主动脉弓重建技术,以避免再狭窄、确保冠状动脉灌注和改善长期结果。在弓内,会产生复杂的湍流;然而,对于不利的低效流动的原因以及避免这种流动的手术技术知之甚少。
我们为 9 名接受不同类型弓重建方法的患者创建了特定于患者的计算血流动力学模型。4 名患者患有主动脉瓣闭锁不全,5 名患者患有主动脉瓣狭窄。使用体表面积校正的超声心动图数据定义血流轮廓。使用有限体积法分析脉动湍流。计算血流能量损失以估计心脏工作量,并计算壁切应力以估计血管壁僵硬度增加。
再狭窄和急性弓角度增加了壁切应力和能量损失。在主动脉瓣闭锁不全的患者中,朝向降主动脉的纵向切口有效地创建了平滑的弓角度。在主动脉瓣狭窄的患者中,在单个吻合部位进行的 Damus-Kaye-Stansel 手术的弓修复有效地创建了足够的吻合空间和平滑的弓角度。
创建大的吻合空间和平滑的主动脉弓角度可降低壁切应力和能量损失,应改善 Norwood 手术后的长期心脏功能。