硝烯基香豆素作为生物硫醇的比色和荧光双探针。
Nitroolefin-based coumarin as a colorimetric and fluorescent dual probe for biothiols.
机构信息
School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
出版信息
Chem Commun (Camb). 2011 Oct 21;47(39):11029-31. doi: 10.1039/c1cc14299b. Epub 2011 Sep 12.
PMID:21909533
Abstract
A coumarin-based thiol probe featuring the 1,4-addition reaction of thiols to nitroolefin was reported. The molecular probe exhibited higher selectivity toward biothiols (Cys, Hcy and GSH) than other amino acids.
摘要
报道了一种基于香豆素的硫醇探针，其特征在于硫醇与硝基烯烃的 1,4-加成反应。该分子探针对生物硫醇（半胱氨酸、高半胱氨酸和谷胱甘肽）的选择性高于其他氨基酸。
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