札幌市神经母细胞瘤的发病率。

Incidence of neuroblastoma in Sapporo city.

作者信息

Nishi M, Miyake H, Takeda T, Shimada M, Takasugi N, Sato Y, Hanai J

机构信息

Department of Public Health, Sapporo Medical College, Japan.

出版信息

J Pediatr Surg. 1990 May;25(5):545-6. doi: 10.1016/0022-3468(90)90570-y.

DOI:10.1016/0022-3468(90)90570-y

PMID:2191108

Abstract

The incidence of neuroblastoma in Sapporo City for the period before the enforcement of the mass screening of neuroblastoma (1974 to 1980) was compared with the period after it (1981 to 1987). No large difference was found in incidence between them. In 1981 to 1987 the occurrence cluster at 2 to 4 years of age found in the prescreening period disappeared and an accumulation of patients at 0 year of age was noted. The sensitivity of the mass screening was almost stable (76.9% to 80.0%) throughout the 7 years. By the mass screening system of Sapporo City, early detection will be expected in 60% to 70% of all the neuroblastoma patients, the deficiency of which is due to the patients who neglected the mass screening.

摘要

将札幌市在实施神经母细胞瘤大规模筛查之前（1974年至1980年）和之后（1981年至1987年）的神经母细胞瘤发病率进行了比较。两者发病率未发现显著差异。在1981年至1987年期间，筛查前发现的2至4岁发病聚集现象消失，0岁患者出现聚集。大规模筛查的敏感度在7年期间几乎保持稳定（76.9%至80.0%）。通过札幌市的大规模筛查系统，预计所有神经母细胞瘤患者中有60%至70%能被早期发现，其不足之处在于部分患者忽视了大规模筛查。