Bonner T J, Eardley W G P, Patterson P, Gregg P J
Queen Elizabeth Hospital, Sheriff Hill, Gateshead, Tyne and Wear NE9 6SX, UK.
J Bone Joint Surg Br. 2011 Sep;93(9):1217-22. doi: 10.1302/0301-620X.93B9.26573.
Correct positioning and alignment of components during primary total knee replacement (TKR) is widely accepted to be an important predictor of patient satisfaction and implant durability. This retrospective study reports the effect of the post-operative mechanical axis of the lower limb in the coronal plane on implant survival following primary TKR. A total of 501 TKRs in 396 patients were divided into an aligned group with a neutral mechanical axis (± 3°) and a malaligned group where the mechanical axis deviated from neutral by > 3°. At 15 years' follow-up, 33 of 458 (7.2%) TKRs were revised for aseptic loosening. Kaplan-Meier survival analysis showed a weak tendency towards improved survival with restoration of a neutral mechanical axis, but this did not reach statistical significance (p = 0.47). We found that the relationship between survival of a primary TKR and mechanical axis alignment is weaker than that described in a number of previous reports.
初次全膝关节置换术（TKR）过程中组件的正确定位和对线被广泛认为是患者满意度和植入物耐用性的重要预测指标。这项回顾性研究报告了初次TKR后下肢冠状面术后机械轴对植入物存活的影响。396例患者的共501例TKR被分为机械轴中立（±3°）的对线组和机械轴偏离中立> 3°的对线不良组。在15年的随访中，458例TKR中有33例（7.2%）因无菌性松动而翻修。Kaplan-Meier生存分析显示，恢复中立机械轴有微弱的生存改善趋势，但未达到统计学意义（p = 0.47）。我们发现，初次TKR的存活与机械轴对线之间的关系比之前一些报告中描述的要弱。
