Tarbaeva D A, Kostinov M P, Iozefson S A, Zagorodnyaya E D
Zh Mikrobiol Epidemiol Immunobiol. 2011 Jul-Aug(4):71-6.
Study of course of pregnancy, delivery, postpartum period and perinatal outcomes in pregnant women with influenza A (H1N1) 2009.
Course of pregnancy and outcomes in 16 women, who had influenza A (H1N1) 2009, were analyzed. Influenza A (H1N1) 2009 virus was detected by PCR.
Influenza A (H1N1) 2009 had a severe course and high rates of complications: pneumonia (100%), respiratory distress syndrome (25%), placental deficiency (100%). Most of the neonates (87%) from mothers, who had influenza A (H1N1) 2009, had neonatal period disorders: congenital pneumonia--2 (12.5%), cerebral ischemia--10 (62.5%), hyperbilirubinemia--2 (12.5%), vegeto-visceral syndrome--4 (25%), hemorrhagic, convulsive and respiratory distress syndrome--1 (6.7%) each. Alteration in placenta was detected--influenza placentitis. Transplacental route of virus transmission was not detected.
Pregnant women are a high risk group for influenza and serious complications caused by the virus. Influenza A (H1N1) 2009 has a more severe course and a higher rate of complications in both mothers and neonates.
