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[心脏肿瘤、缩窄性心包炎和肺血栓栓塞]

[Cardiac tumor, constrictive pericarditis and pulmonary thromboembolism].

作者信息

Takano Tamaki, Amano Jun

机构信息

Department of Cardiovascular Surgery, Shinshu University, Matsumoto, Japan.

出版信息

Kyobu Geka. 2011 Jul;64(8 Suppl):658-65.

Abstract

Cardiac tumors are rare, and 3-quarters of these tumors are benign and nearly half of the benign tumors are myxomas. Metastases to the heart are more common than primary cardiac tumors. Cardiac tumors present obstructive, constitutional and embolic signs and symptoms. Echocardiograms, chest computed tomography (CT) and magnetic resonance imaging (MRI) scan are very useful for diagnosis. Surgery is indicated in patients with benign tumor, and chemo/radio-therapy in patients with malignant tumors. Prognosis after surgery is good, instead poor prognosis for patients with malignancy. Constrictive pericarditis is mainly result of idiopathic, previous cardiac surgery and radiation in recent years. Diagnosis is made by echo cardiography and cardiac catheterization along with clinical presentation. Thickened pericardium is directly diagnosed by currently advanced transesophageal echocardiography, CT and MRI although normal thickness of the pericardium with constrictive pericarditis is observed in some patients. Pericardiectomy is the only treatment for permanent constriction. The incidence of pulmonary thromboembolism is currently increasing in Japan. Guidelines for the diagnosis, treatment and prevention of pulmonary thromboembolism and deep vein thrombosis (JCS 2009) is helpful for diagnosis and treatment decision. Anticoagulant is initial treatment for acute pulmonary thromboembolism, and intravenous thrombolysis is performed in hemodynamically unstable cases. Chronic thromboembolic pulmonary hypertention is treated by pulmonary endarterectomy whereas anticoagulant and vasodilator are used for peripheral type and mild cases.

摘要

心脏肿瘤较为罕见,其中四分之三的肿瘤为良性,且近一半的良性肿瘤是黏液瘤。心脏转移瘤比原发性心脏肿瘤更为常见。心脏肿瘤会出现梗阻性、全身性和栓塞性体征及症状。超声心动图、胸部计算机断层扫描(CT)和磁共振成像(MRI)扫描对诊断非常有用。良性肿瘤患者需进行手术,恶性肿瘤患者则需进行化疗/放疗。手术后预后良好,而恶性肿瘤患者预后较差。缩窄性心包炎主要是由特发性、既往心脏手术以及近年来的放疗引起的。通过超声心动图、心导管检查以及临床表现进行诊断。尽管部分缩窄性心包炎患者心包厚度正常,但目前先进的经食管超声心动图、CT和MRI可直接诊断增厚的心包。心包切除术是治疗永久性缩窄的唯一方法。目前日本肺血栓栓塞症的发病率正在上升。《肺血栓栓塞症和深静脉血栓形成的诊断、治疗及预防指南(2009年日本循环学会)》有助于诊断和治疗决策。抗凝治疗是急性肺血栓栓塞症的初始治疗方法,血流动力学不稳定的病例需进行静脉溶栓治疗。慢性血栓栓塞性肺动脉高压通过肺动脉内膜剥脱术治疗,而外周型和轻度病例则使用抗凝剂和血管扩张剂治疗。

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