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腹腔镜耻骨固定术治疗盆腔器官脱垂:501 例患者系列中 10 年的单中心经验。

Laparoscopic promontofixation for pelvic organ prolapse: a 10-year single center experience in a series of 501 patients.

机构信息

Department of Urology, Clinique Chirurgicale du Pré, Le Mans, France.

出版信息

Int J Urol. 2011 Dec;18(12):821-6. doi: 10.1111/j.1442-2042.2011.02857.x. Epub 2011 Sep 14.

Abstract

OBJECTIVES

To assess the long-term outcomes of laparoscopic promontofixation (LP) for the treatment of pelvic organ prolapse (POP).

METHODS

A total of 501 consecutive patients with POP were included in this prospective study. The patients' mean age was 63.23 (36-90) years, their mean body mass index was 25.14 (15-36) and their mean number of deliveries was 3.3 (0-14). A POP grade ≥3 was diagnosed in 70.4% of the patients and 38.9% of them had a history of abdominal surgery. The patients underwent a Bonney test and urodynamic study. In cases of stress urinary incontinence (SUI), the patients underwent the simultaneous insertion of a tension-free vaginal tape. A prolapse quality of life questionnaire was sent to all patients.

RESULTS

The mean operative time was 97.4 min (50-210) and there were 1.7% cases of intra-operative complications. The mean hospitalization time was 3.7 days (1-13 days). During the mean follow-up of 20.7 months (3-120), 91 (17.8%) complications were recorded, including constipation (5.5%), SUI (3.5%), vaginal erosion (2.4%), and urge incontinence (2%). Recurrences were recorded in 11.5% of the patients within an average time of 37.2 months. Risk factors for recurrence were the use of the polypropylene mesh compared with the polyester mesh (P<0.0001), an intra-operative hysterectomy (P=0.02), and bleeding (P=0.049). There was a statistical significant (P<0.001) improvement in most of the symptoms in the prolapse quality of life questionnaire.

CONCLUSIONS

LP is safe with effective long-term results, with low recurrence and morbidity rates, and a good quality of life.

摘要

目的

评估腹腔镜耻骨固定术(LP)治疗盆腔器官脱垂(POP)的长期疗效。

方法

本前瞻性研究共纳入 501 例 POP 患者。患者的平均年龄为 63.23(36-90)岁,平均体重指数为 25.14(15-36),平均分娩次数为 3.3(0-14)次。70.4%的患者诊断为 POP 分级≥3,38.9%的患者有腹部手术史。患者接受了 Bonney 测试和尿动力学研究。对于压力性尿失禁(SUI)患者,同时植入了无张力阴道吊带。所有患者均发送了脱垂生活质量问卷。

结果

平均手术时间为 97.4 分钟(50-210 分钟),术中并发症发生率为 1.7%。平均住院时间为 3.7 天(1-13 天)。在平均 20.7 个月(3-120 个月)的随访期间,记录了 91 例(17.8%)并发症,包括便秘(5.5%)、SUI(3.5%)、阴道侵蚀(2.4%)和急迫性尿失禁(2%)。在平均 37.2 个月的时间内,有 11.5%的患者出现复发。复发的危险因素是使用聚丙烯网与聚酯网相比(P<0.0001)、术中子宫切除术(P=0.02)和出血(P=0.049)。在脱垂生活质量问卷中,大多数症状都有显著的统计学意义(P<0.001)改善。

结论

LP 安全有效,长期效果好,复发率和发病率低,生活质量高。

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