A型肉毒毒素在脑瘫患儿治疗中的应用。
Use of botulinum toxin A in management of children with cerebral palsy.
机构信息
BC Children's Hospital, Department of Pediatrics, Vancouver, BC V6H 3V4, Canada.
出版信息
Can Fam Physician. 2011 Sep;57(9):1006-73.
Abstract
QUESTION
What is the role of intramuscular botulinum toxin injections in the management of spasticity and related morbidity in children with cerebral palsy?
ANSWER
When botulinum toxin A is injected into the limbs of children with spastic paresis, it induces temporary reduction in muscle tone. It also promotes better motor function when used in combination with conservative treatments such as physiotherapy. Although there is a growing body of evidence for its effective and safe treatment, there is still a lack of consensus on dose, treatment regimens, and the best integration with other clinical modalities.
摘要
问题
肌内注射肉毒毒素在脑瘫儿童痉挛及其相关发病率的管理中的作用是什么？
答案
当肉毒毒素 A 注射到痉挛性弛缓患儿的四肢时，会导致肌肉张力暂时降低。当与物理疗法等保守治疗联合使用时，它还可以促进更好的运动功能。尽管越来越多的证据表明其治疗有效且安全，但在剂量、治疗方案以及与其他临床方式的最佳结合方面仍缺乏共识。
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