General Adult Psychiatry, Parkhead Hospital, Glasgow G315EB, United Kingdom.
Addict Behav. 2012 Jan;37(1):124-6. doi: 10.1016/j.addbeh.2011.08.005. Epub 2011 Aug 25.
A significant number of men with opiate misuse have sexual problems. Premature ejaculation (PE) occurs predominantly on discontinuation of the opiate but seems to persist in some cases. The aims of this study were to determine the rates of PE and other sexual dysfunctions in patients maintained on methadone; to determine the time of onset of PE in relation to onset of opiate misuse; and to look at the patients' perception of the effect of heroin and methadone on PE.
Sixty five men attending a tertiary referral clinic for methadone maintenance treatment were assessed cross-sectionally using a semi-structured questionnaire, clinical interview, review of clinical records and the International Index of Erectile Function (IIEF).
Thirty eight (58.5%) subjects reported a "lifetime" history of PE. Twenty (30.76%) of them reported "current" history of PE. Eleven (16.9%) people reported that PE preceded opiate misuse. Twenty four (63.2%) felt that heroin helped their PE and 7 (18.4%) felt that heroin worsened it. Fourteen (36.8%) felt that methadone helped PE, while 10 (26.3%) felt methadone worsened PE. Only 2 out of 65 (3.07%) reported that they had been asked about their sex life by the addiction services.
Prevalence of "current" premature ejaculation was almost 3 times greater than reported in the general population. A significant number of patients perceived heroin to be beneficial on PE. Presence of sexual dysfunction could therefore be a risk factor for relapse into heroin misuse. Most clinicians avoid asking patients questions of a sexual nature. Nevertheless, managing sexual difficulties among patients with opiate misuse could be a significant step in relapse prevention.
大量滥用阿片类药物的男性存在性问题。早泄(PE)主要发生在阿片类药物停药时,但在某些情况下似乎仍持续存在。本研究旨在确定接受美沙酮维持治疗的患者中 PE 及其他性功能障碍的发生率;确定 PE 与阿片类药物滥用开始时间的关系;并观察患者对海洛因和美沙酮对 PE 的影响的看法。
65 名在三级转诊诊所接受美沙酮维持治疗的男性患者通过半结构式问卷、临床访谈、临床记录回顾和国际勃起功能指数(IIEF)进行了横断面评估。
38 名(58.5%)患者报告有“终生”PE 病史。其中 20 名(30.76%)报告“当前”PE 病史。11 名(16.9%)人报告 PE 先于阿片类药物滥用。24 人(63.2%)认为海洛因有助于他们的 PE,7 人(18.4%)认为海洛因使 PE 恶化。14 人(36.8%)认为美沙酮有助于 PE,而 10 人(26.3%)认为美沙酮使 PE 恶化。在 65 名患者中,只有 2 名(3.07%)报告他们的性健康问题曾被成瘾服务机构询问过。
“当前”早泄的患病率几乎是普通人群报告的 3 倍。相当数量的患者认为海洛因对 PE 有益。因此,性功能障碍的存在可能是复吸海洛因的风险因素。大多数临床医生避免询问患者与性有关的问题。然而,管理阿片类药物滥用患者的性困难可能是预防复发的重要步骤。