Kiziltepe State Hospital, Kiziltepe, Mardin, Turkey.
J Sex Med. 2011 Apr;8(4):1177-85. doi: 10.1111/j.1743-6109.2010.02183.x. Epub 2011 Jan 26.
In addition to the previously defined "lifelong" and "acquired" premature ejaculation (PE), the existence of two more subtypes of PE, namely "natural variable PE" and "premature-like ejaculatory dysfunction," has been proposed.
To evaluate the diagnostic value of the Premature Ejaculation Diagnostic Tool (PEDT) and Arabic Index of Premature Ejaculation (AIPE) in a population-based study, in relation to their sensitivity across these four different PE syndromes and to assess the Premature Ejaculation Profile (PEP) scores of patients with lifelong, acquired, natural variable PE and premature-like ejaculatory dysfunction.
Between June 2009 and December 2009, couples were randomly selected from 17 provinces of Turkey. Subjects with the complaint of ejaculating prematurely were classified as lifelong, acquired, natural variable PE, and premature-like ejaculatory dysfunction according to the medical and sexual history they described. PE status was also assessed with PEDT, AIPE and PEP. The sensitivity, specificity, positive predictive value and negative predictive value were calculated for PEDT and AIPE in the study population whereas detection rates of these two questionnaires were also compared among the four PE syndromes. Moreover, PEP scores of patients with lifelong, acquired, natural variable PE and premature-like ejaculatory dysfunction were compared. Significance level was considered as P < 0.05.
Scores obtained from PEDT, AIPE, and PEP questionnaires.
A total of 2,593 couples were enrolled where 512 (20.0%) male subjects reported PE. PEDT, AIPE, and PEP measures of the PE patients indicated worse sexual function (P < 0.001 each). Mean scores obtained from questionnaires were significantly better in patients with premature-like ejaculatory dysfunction and they were the worst in patients with acquired PE (P < 0.001 each). The sensitivity values of PEDT and AIPE were 89.3 and 89.5, whereas their specificity values were 50.5 and 39.1, respectively. There were statistically significant differences in detection rates of PEDT and AIPE among the four PE syndromes (P = 0.006 and P < 0.001). They were higher in acquired and lifelong PE and lower in premature-like ejaculatory dysfunction.
PEDT and AIPE can diagnose PE with high sensitivity, especially in patients with lifelong and acquired PE. The complaint of patients with acquired PE seems to be more severe than those complaining of lifelong, natural variable PE and premature-like ejaculatory dysfunction patients.
除了先前定义的“终身”和“获得性”早泄(PE)之外,还提出了另外两种 PE 亚型,即“自然变量 PE”和“类似早泄的性功能障碍”。
在一项基于人群的研究中,评估早泄诊断工具(PEDT)和阿拉伯早泄指数(AIPE)的诊断价值,以及它们在这四种不同的 PE 综合征中的敏感性,并评估终身、获得性、自然变量 PE 和类似早泄的性功能障碍患者的早泄特征量表(PEP)评分。
2009 年 6 月至 2009 年 12 月,从土耳其的 17 个省中随机选择夫妇。根据他们所描述的医学和性史,将抱怨射精过早的患者归类为终身、获得性、自然变量 PE 和类似早泄的性功能障碍。使用 PEDT、AIPE 和 PEP 评估 PE 状况。在研究人群中计算 PEDT 和 AIPE 的灵敏度、特异性、阳性预测值和阴性预测值,并比较这两种问卷在四种 PE 综合征中的检出率。此外,还比较了终身、获得性、自然变量 PE 和类似早泄的性功能障碍患者的 PEP 评分。显著性水平设为 P < 0.05。
PEDT、AIPE 和 PEP 问卷的得分。
共纳入 2593 对夫妇,其中 512 名(20.0%)男性报告有 PE。PE 患者的 PEDT、AIPE 和 PEP 措施表明性功能更差(每项 P < 0.001)。来自问卷的平均得分在类似早泄的性功能障碍患者中明显更好,而在获得性 PE 患者中最差(每项 P < 0.001)。PEDT 和 AIPE 的灵敏度值分别为 89.3%和 89.5%,而特异性值分别为 50.5%和 39.1%。PEDT 和 AIPE 在四种 PE 综合征中的检出率有统计学差异(P = 0.006 和 P < 0.001)。在获得性和终身性 PE 中较高,在类似早泄的性功能障碍中较低。
PEDT 和 AIPE 可高度敏感地诊断 PE,尤其是在患有终身性和获得性 PE 的患者中。获得性 PE 患者的抱怨似乎比终身性、自然变量 PE 和类似早泄的性功能障碍患者更严重。