Tokuyasu Hirokazu, Sakaguchi Yasuto, Isowa Noritaka, Izumi Hiroki, Takeda Kenichi, Miura Hiroshi, Shimizu Eiji
Division of Respiratory Medicine, Matsue Red Cross Hospital, Japan.
Intern Med. 2011;50(18):2003-6. doi: 10.2169/internalmedicine.50.5526. Epub 2011 Sep 15.
A 67-year-old man was referred to our hospital for a detailed medical examination of a bronchial polyp that was detected during chest computed tomography. Bronchoscopic examination revealed a tumor that almost occluded the main left bronchus. Nd-YAG laser treatment and tumor removal with biopsy forceps were conducted. On the basis of the histopathological and immunohistochemical features, large cell neuroendocrine carcinoma (LCNEC), T2aN0M0, stage IB was diagnosed. After induction chemotherapy with a combination of cisplatin and etoposide, a sleeve resection of the left main bronchus with telescoping bronchial anastomosis was performed. LCNEC typically occurs in the peripheral lung field, but here, we report a rare case of LCNEC arising from the left main bronchus.
一名67岁男性因胸部计算机断层扫描发现支气管息肉而被转诊至我院进行详细的医学检查。支气管镜检查发现一个几乎阻塞左主支气管的肿瘤。进行了钕钇铝石榴石激光治疗并用活检钳切除肿瘤。根据组织病理学和免疫组化特征，诊断为大细胞神经内分泌癌（LCNEC），T2aN0M0，ⅠB期。在顺铂和依托泊苷联合诱导化疗后，进行了左主支气管袖状切除术并进行了套入式支气管吻合。LCNEC通常发生在肺外周野，但在此，我们报告了一例罕见的起源于左主支气管的LCNEC病例。
