Cleveland, Ohio From the Department of Plastic and Reconstructive Surgery, Rainbow Babies and Children's Hospital, University Hospitals Case Medical Center, Case Western Reserve University.
Plast Reconstr Surg. 2011 Oct;128(4):328e-334e. doi: 10.1097/PRS.0b013e3182268c54.
The incidence of craniopagus twins approximates four to six per 10 million births. Although rare, surgical separation of conjoined twins poses significant technical and ethical challenges. The present report uses the case of craniopagus twins AD and TD to examine the bioethical issues faced by a multidisciplinary medical team in planning the separation of craniopagus twins. AD and TD are craniopagus twins conjoined at the head. TD's head is conjoined to the back of AD's head. Neurologically, AD has the dominant cerebral circulation. TD has two normal kidneys, whereas AD has none. AD depends on TD's renal function and, on separation, will require either a kidney transplant or lifelong dialysis. This case report reviews one approach to analyzing and solving complex ethical dilemmas in pediatric plastic surgery. The principles reviewed are (1) autonomy and informed consent, focusing especially on the role of children in the informed consent process; (2) beneficence and nonmaleficence, two intricately intertwined principles because separation could potentially cause irreversible harm to one twin while improving the quality of life for the other (as separation is not a life-saving procedure, is it ethical to perform a procedure with unknown surgical risk to improve children's quality of life?); and (3) justice (is it fair to allocate excessive medical resources for the twins' separation?). The present report explores the ethics behind such decisions with respect to the separation of conjoined twins.
双头畸胎的发病率约为每百万出生婴儿中有四到六个。尽管罕见,但联体双胞胎的手术分离具有重大的技术和伦理挑战。本报告使用双头畸胎 AD 和 TD 的病例,探讨了多学科医疗团队在规划双头畸胎分离时面临的生物伦理问题。AD 和 TD 是头部相连的双头畸胎。TD 的头部与 AD 的后脑勺相连。在神经学上,AD 具有优势的大脑循环。TD 有两个正常的肾脏,而 AD 则没有。AD 依赖 TD 的肾功能,在分离后,将需要进行肾移植或终身透析。本病例报告回顾了一种分析和解决小儿整形外科中复杂伦理困境的方法。回顾的原则是:(1)自主性和知情同意,特别关注儿童在知情同意过程中的作用;(2)善行和不伤害,这两个原则紧密交织,因为分离可能对一个双胞胎造成不可逆转的伤害,同时改善另一个双胞胎的生活质量(由于分离不是挽救生命的程序,那么为了提高儿童的生活质量而进行具有未知手术风险的手术是否合乎道德?);以及(3)公正(为双胞胎的分离分配过多的医疗资源是否公平?)。本报告探讨了在联体双胞胎分离方面这些决策背后的伦理问题。