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阻塞性睡眠呼吸暂停综合征:机动车驾驶员的风险评估与管理。

Obstructive sleep apnea syndrome: assessing and managing risk in the motor vehicle operator.

机构信息

Department of Medicine, Division of Pulmonary, Critical Care, & Sleep Disorders Medicine, University of Louisville, Louisville, Kentucky 40202, USA.

出版信息

Curr Opin Pulm Med. 2011 Nov;17(6):412-8. doi: 10.1097/MCP.0b013e32834b96a4.

DOI:10.1097/MCP.0b013e32834b96a4
PMID:21921796
Abstract

PURPOSE OF REVIEW

Obstructive sleep apnea (OSA) is a common condition that can significantly affect daytime functioning, leading to excessive daytime sleepiness and fatigue. Motor vehicle crashes are common, resulting in financial burden, property loss, injury, and death. Motor vehicle operators are at increased risk for crash in the context of excessive daytime sleepiness and fatigue, largely due to inattention. The physician caring for individuals with risk of or diagnosed OSA must be aware of the potentially increased risk for motor vehicle crashes, especially in professional drivers. Because of empiric data on increased risk for crashes in commercial vehicle operators, the importance of identifying OSA has become the subject of focused attention by the Federal Motor Carrier Safety Administration (FMCSA). A task force has published recommendations for clinical care and urged further research on the interplay between sleep apnea, sleepiness, and crash risk.

RECENT FINDINGS

Despite the logical relationship between OSA and motor vehicle crashes, data to support this theory remain of overall modest quality. Recent case-control and cohort studies continue to produce supportive evidence. Additionally, several meta-analyses of past studies have supported the crash risk associated with OSA and confirmed improvement with effective treatment using continuous positive airway pressure.

SUMMARY

Further study is needed to more fully characterize the interplay between sleepiness and OSA, the crash risk associated with untreated OSA, and the benefit of treatment on reducing crash risk. For now, empiric recommendations are offered to screen and manage all individuals who drive, particularly those who drive professionally.

摘要

目的综述

阻塞性睡眠呼吸暂停(OSA)是一种常见病症,可显著影响白天的机能,导致日间过度嗜睡和疲劳。机动车事故较为常见,造成经济负担、财产损失、伤害和死亡。在日间过度嗜睡和疲劳的情况下,机动车驾驶员发生事故的风险增加,主要是因为注意力不集中。对于有 OSA 风险或确诊 OSA 的个体,负责治疗的医生必须意识到发生机动车事故的潜在风险增加,尤其是职业驾驶员。由于商业机动车驾驶员发生事故的风险增加存在经验数据,美国联邦汽车运输安全管理局(FMCSA)开始关注识别 OSA 的重要性。一个工作组发布了临床护理建议,并敦促进一步研究睡眠呼吸暂停、嗜睡和事故风险之间的相互作用。

最新发现

尽管 OSA 和机动车事故之间存在逻辑关系,但支持这一理论的数据总体质量仍较低。最近的病例对照和队列研究继续提供支持性证据。此外,几项对过去研究的荟萃分析也支持了与 OSA 相关的事故风险,并证实了使用持续气道正压通气进行有效治疗可降低风险。

总结

需要进一步研究以更全面地描述嗜睡和 OSA 之间的相互作用、未经治疗的 OSA 相关的事故风险,以及治疗对降低事故风险的益处。目前,针对所有驾驶人员,特别是职业驾驶员,提出了经验性的筛查和管理建议。

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