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1
Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors.
Curr Opin Struct Biol. 2011 Oct;21(5):583-9. doi: 10.1016/j.sbi.2011.08.008. Epub 2011 Sep 15.
2
Notch signaling in normal and disease States: possible therapies related to glycosylation.
Curr Mol Med. 2007 Jun;7(4):427-45. doi: 10.2174/156652407780831593.
3
Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila.
Cell Rep. 2019 Nov 12;29(7):2054-2066.e6. doi: 10.1016/j.celrep.2019.10.027.
5
Modulation of receptor signaling by glycosylation: fringe is an O-fucose-beta1,3-N-acetylglucosaminyltransferase.
Biochim Biophys Acta. 2002 Dec 19;1573(3):328-35. doi: 10.1016/s0304-4165(02)00400-2.
6
Multiple roles for O-glycans in Notch signalling.
FEBS Lett. 2018 Dec;592(23):3819-3834. doi: 10.1002/1873-3468.13251. Epub 2018 Nov 28.
7
Glycosylation regulates Notch signalling.
Nat Rev Mol Cell Biol. 2003 Oct;4(10):786-97. doi: 10.1038/nrm1228.
8
Biological functions of glycosyltransferase genes involved in O-fucose glycan synthesis.
J Biochem. 2008 Jul;144(1):1-6. doi: 10.1093/jb/mvn016. Epub 2008 Feb 13.
9
Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe.
J Biol Chem. 2002 Aug 16;277(33):29945-52. doi: 10.1074/jbc.M204445200. Epub 2002 May 29.
10
Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch.
J Biol Chem. 2016 Jul 29;291(31):16348-60. doi: 10.1074/jbc.M116.732537. Epub 2016 Jun 6.

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POFUT1 as a cancer biomarker: insights into its oncogenic mechanisms and clinical relevance.
J Mol Med (Berl). 2025 Aug 7. doi: 10.1007/s00109-025-02578-1.
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Deciphering the molecular drivers for cashmere/pashmina fiber production in goats: a comprehensive review.
Mamm Genome. 2025 Mar;36(1):162-182. doi: 10.1007/s00335-025-10109-z. Epub 2025 Feb 4.
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Manic Fringe promotes endothelial-to-mesenchymal transition mediated by the Notch signalling pathway during heart valve development.
J Mol Med (Berl). 2025 Jan;103(1):51-71. doi: 10.1007/s00109-024-02492-y. Epub 2024 Nov 11.
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Par3/bazooka binds NICD and promotes notch signaling during Drosophila development.
Dev Biol. 2024 Oct;514:37-49. doi: 10.1016/j.ydbio.2024.06.009. Epub 2024 Jun 15.
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Notch signaling pathway in cancer: from mechanistic insights to targeted therapies.
Signal Transduct Target Ther. 2024 May 27;9(1):128. doi: 10.1038/s41392-024-01828-x.
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Genetics of glycosylation in mammalian development and disease.
Nat Rev Genet. 2024 Oct;25(10):715-729. doi: 10.1038/s41576-024-00725-x. Epub 2024 May 9.
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Novel insight into FCSK-congenital disorder of glycosylation through a CRISPR-generated cell model.
Mol Genet Genomic Med. 2024 May;12(5):e2445. doi: 10.1002/mgg3.2445.

本文引用的文献

1
O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1.
J Biol Chem. 2011 Sep 9;286(36):31623-37. doi: 10.1074/jbc.M111.268243. Epub 2011 Jul 8.
2
Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi.
Development. 2011 May;138(10):1925-34. doi: 10.1242/dev.060020. Epub 2011 Apr 13.
5
Roles of glycosylation in Notch signaling.
Curr Top Dev Biol. 2010;92:131-64. doi: 10.1016/S0070-2153(10)92004-8.
6
Regulation of notch signaling via O-glucosylation insights from Drosophila studies.
Methods Enzymol. 2010;480:375-98. doi: 10.1016/S0076-6879(10)80017-5.
7
O-GlcNAc modification of the extracellular domain of Notch receptors.
Methods Enzymol. 2010;480:355-73. doi: 10.1016/S0076-6879(10)80016-3.
9
Role of glycans and glycosyltransferases in the regulation of Notch signaling.
Glycobiology. 2010 Aug;20(8):931-49. doi: 10.1093/glycob/cwq053. Epub 2010 Apr 5.
10
Role of glycosylation of Notch in development.
Semin Cell Dev Biol. 2010 Aug;21(6):638-45. doi: 10.1016/j.semcdb.2010.03.003. Epub 2010 Mar 10.

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