Clínica Clofan, Clínica Oftalmológica de Medellín (COM), Medellín, Colombia.
Cornea. 2011 Nov;30(11):1201-6. doi: 10.1097/ICO.0b013e3182182bc6.
To compare astigmatism correction using shorter arc length 90°/120° asymmetric Intacs severe keratoconus (SK) versus 150° single-segment Intacs SK in cases of asymmetric keratoconus.
Retrospective prospective study in patients of asymmetric keratoconus with more than 2 diopters (D) of refractive astigmatism. Group 1 included 16 eyes of 16 patients who underwent 150° single-segment Intacs SK implantation, and group 2 included 16 eyes of 12 patients who underwent asymmetric shorter arc length 90°/120° Intacs SK implantation. Patients younger than 35 years were cross-linked. Parameters studied included preoperative and postoperative (1 and 9 months) uncorrected distance visual acuity (UDVA), best corrected distance visual acuity (CDVA), manifest refraction, and corneal topography.
Both groups demonstrated significant improvement in UDVA, CDVA, spherical equivalent (SE), and manifest cylinder after the surgery. Comparison of change (post-pre) in UDVA, CDVA, and SE at the 1- and 9-month postoperative visits demonstrated significant improvement without statistically significant difference between the 2 groups. However, change in manifest cylinder at 1 month was statistically significantly higher in group 2 (4.65 ± 2.21 D) versus group 1 (2.29 ± 1.57 D) (P = 0.001). At the 9-month visit, change in manifest cylinder continued to be higher at 3.43 ± 1.79 D in group 2 versus 2.58 ± 1.29 D in group 1; however, this difference was not statistically significant (P = 0.17).
Implantation of asymmetric shorter arc length 90°/120° Intacs SK segments achieved 33% higher correction of astigmatism compared with 150° single-segment Intacs SK implantation. Improvement in UDVA, CDVA, and SE was comparable.
比较使用较短的弧形长度 90°/120°不对称 Intacs 严重圆锥角膜(SK)与 150°单段 Intacs SK 矫正不对称性圆锥角膜的散光。
回顾性前瞻性研究患有超过 2 屈光度(D)屈光性散光的不对称性圆锥角膜患者。第 1 组包括 16 例 16 只眼,行 150°单段 Intacs SK 植入术;第 2 组包括 12 例 16 只眼,行不对称较短弧形长度 90°/120°Intacs SK 植入术。35 岁以下的患者行交联术。研究参数包括术前、术后 1 个月和 9 个月的未矫正距离视力(UDVA)、最佳矫正距离视力(CDVA)、客观验光和角膜地形图。
两组术后 UDVA、CDVA、球镜等效(SE)和角膜散光均显著改善。术后 1 个月和 9 个月 UDVA、CDVA 和 SE 的变化(术后-术前)比较显示,两组均有显著改善,但差异无统计学意义。然而,第 2 组术后 1 个月的角膜散光变化明显高于第 1 组(4.65±2.21 D 比 2.29±1.57 D)(P=0.001)。术后 9 个月,第 2 组角膜散光变化仍较高,为 3.43±1.79 D,第 1 组为 2.58±1.29 D;然而,差异无统计学意义(P=0.17)。
植入不对称较短弧形长度 90°/120°Intacs SK 段可矫正散光,较 150°单段 Intacs SK 植入术矫正率高 33%。UDVA、CDVA 和 SE 的改善相当。