Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Ontario, Canada.
J Cataract Refract Surg. 2010 Jan;36(1):110-3. doi: 10.1016/j.jcrs.2009.07.040.
To report the efficacy and safety of intrastromal corneal ring segment (ICRS) implantation using a femtosecond laser in the management of advanced keratoconus.
Private laser center, Toronto, Ontario, Canada.
In this retrospective nonrandomized study, Intacs SK ICRS were implanted using an IntraLase femtosecond laser in eyes with moderate to severe keratoconus. Evaluation included uncorrected (UDVA) and corrected (CDVA) distance visual acuity, manifest refraction, slitlamp examination, corneal topography, and wavefront analysis of higher-order aberrations. Postoperative visits were at 1, 7, and 30 days and 3 and 6 months.
The study evaluated 10 eyes of 8 patients with a mean age of 28 years (range 21 to 42 years). The mean UDVA was significantly better 6 months postoperatively than preoperatively (0.66 logMAR +/- 0.21 [SD] versus 1.19 +/- 0.57 logMAR) (P = .004), as was the mean CDVA (0.25 +/- 0.15 logMAR versus 0.51 +/- 0.20 logMAR) (P = .018). The mean spherical equivalent refractive error was -8.08 diopters (D) preoperatively and -5.03 D at 6 months (P = .65); the mean refractive astigmatism, -5.05 D and -3.90 D, respectively (P = .22); and the mean simulated keratometry value, 57.94 D and 50.07 D, respectively (P = .15). The mean total aberration improved significantly, from 13.48 +/- 4.64 mum preoperatively to 9.42 +/- 1.80 mum postoperatively (P = .007). There were no complications.
Implantation of ICRS for advanced keratoconus was safe and effective, leading to significant improvement in UDVA, CDVA, and total aberrations.
No author has a financial or proprietary interest in any material or method mentioned.
报告使用飞秒激光行角膜基质内环植入术（ICRS）治疗进展性圆锥角膜的疗效和安全性。
加拿大安大略省多伦多市私立激光中心。
本回顾性非随机研究中，对中重度圆锥角膜患者应用飞秒激光植入 Intacs SK ICRS。评估包括未矫正（UDVA）和矫正（CDVA）远距视力、主觉验光、裂隙灯检查、角膜地形图和高阶像差波前分析。术后 1、7、30 天和 3、6 个月随访。
本研究共纳入 8 例（10 只眼）患者，平均年龄 28 岁（21～42 岁）。术后 6 个月，平均 UDVA 显著优于术前（0.66 logMAR +/- 0.21 [SD] 比 1.19 +/- 0.57 logMAR）（P =.004），平均 CDVA 也显著优于术前（0.25 +/- 0.15 logMAR 比 0.51 +/- 0.20 logMAR）（P =.018）。术前平均等效球镜度数为-8.08 屈光度（D），术后 6 个月为-5.03 D（P =.65）；平均屈光性散光分别为-5.05 D 和-3.90 D（P =.22）；平均模拟角膜曲率值分别为 57.94 D 和 50.07 D（P =.15）。总的像差显著改善，从术前的 13.48 +/- 4.64 mum 降至术后的 9.42 +/- 1.80 mum（P =.007）。无并发症发生。
应用 ICRS 治疗进展性圆锥角膜是安全有效的，可显著提高 UDVA、CDVA 和总像差。
无作者存在任何与材料或方法相关的财务或私人利益。
