Weinbacher F M, Littlejohn C E, Conley P F
Appl Nurs Res. 1990 May;3(2):63-7. doi: 10.1016/s0897-1897(05)80160-0.
Insulin was examined for the rate of bacterial growth after being stored in prefilled syringes in home refrigerators and in a controlled laboratory refrigerator. Home refrigerators were used to simulate conditions that exist in client homes to establish the safety of storing insulin in prefilled syringes in uncontrolled environments. Insulin from each source was inoculated on three different media and incubated at three temperatures in three oxygen environments. A total of 768 cultures were examined. It was found that temperature had a significant effect on the incidence of bacteria. The difference in incident of bacteria between syringes stored in the controlled versus uncontrolled environments was not statistically significant.
对胰岛素进行了研究，观察其在家庭冰箱和受控实验室冰箱中的预填充注射器中储存后的细菌生长速率。使用家庭冰箱模拟客户家中的实际情况，以确定在不受控制的环境中于预填充注射器中储存胰岛素的安全性。将来自每种来源的胰岛素接种在三种不同的培养基上，并在三种氧气环境中的三个温度下进行培养。总共检查了768个培养物。结果发现，温度对细菌的发生率有显著影响。储存在受控环境与不受控环境中的注射器之间的细菌发生率差异无统计学意义。
