Rekate Harold L
Department of Neurosurgery, The Chiari Institute, Hofstra North Shore-LIJ College of Medicine, 865 Northern Blvd., Suite 302, Great Neck, NY 110021, USA.
Childs Nerv Syst. 2011 Oct;27(10):1535-41. doi: 10.1007/s00381-011-1558-y. Epub 2011 Sep 17.
Between 2009 and 2011 an attempt has been made to develop a consensus on the classification of hydrocephalus. Clinicians and basic scientists who are recognized internationally for their work in hydrocephalus attended working meetings in which the concepts of classification of hydrocephalus were discussed at length.
This review attempts to explain the relevance of a classification scheme based on the point of obstruction to the flow of cerebrospinal fluid to basic science research into the pathophysiology and effects of hydrocephalus. The review is designed to give examples of the value of this classification in analyzing research utilizing animal models. The development of hydrocephalus in the absence of a point of obstruction (true communicating hydrocephalus) is analyzed.
Contemporary neuroimaging techniques are now available that can identify the actual point of obstruction to the flow of CSF, if any, which results in the development of hydrocephalus. Such identification may lead to improved ability to analyze animal models used in hydrocephalus research as well as deciding among various treatment options.
2009年至2011年期间，人们试图就脑积水的分类达成共识。在脑积水研究领域具有国际公认地位的临床医生和基础科学家参加了工作会议，会上详细讨论了脑积水的分类概念。
本综述试图解释基于脑脊液流动梗阻点的分类方案与脑积水病理生理学及影响的基础科学研究之间的相关性。该综述旨在举例说明这种分类在分析利用动物模型的研究中的价值。分析了无梗阻点（真性交通性脑积水）情况下脑积水的发生发展。
当代神经影像技术现已能够识别脑脊液流动的实际梗阻点（如有），正是该梗阻点导致了脑积水的发生。这种识别可能会提高分析脑积水研究中所用动物模型的能力，以及在各种治疗方案之间做出决策的能力。
