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婴儿血管瘤:两例普萘洛尔过量病例报告

Haemangioma of infancy: two case reports with an overdose of propranolol.

作者信息

Janmohamed S R, Madern G C, de Laat P C J, Oranje A P

机构信息

Division of Paediatric Dermatology at, University Medical Center, Rotterdam, the Netherlands.

出版信息

Case Rep Dermatol. 2011 Jan;3(1):18-21. doi: 10.1159/000324421. Epub 2011 Feb 5.

DOI:10.1159/000324421
PMID:21931573
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3175358/
Abstract

An 8-week-old infant was treated with oral propranolol for a haemangioma of infancy. The standard dose (according to protocol) is 2 mg/kg/day but, because of a mistake by the pharmacist, the child was treated with 8 mg/kg/day without any side effects (pulse, blood pressure and glucose stayed normal).

摘要

一名8周大的婴儿因患有婴儿血管瘤接受了口服普萘洛尔治疗。标准剂量(根据方案)为2毫克/千克/天,但由于药剂师的失误,该患儿接受了8毫克/千克/天的治疗,且未出现任何副作用(脉搏、血压和血糖均保持正常)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3175358/1e3a3f0689b8/cde0003-0018-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3175358/955767972f93/cde0003-0018-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3175358/1e3a3f0689b8/cde0003-0018-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3175358/955767972f93/cde0003-0018-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f8b/3175358/1e3a3f0689b8/cde0003-0018-f02.jpg

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Haemangioma of infancy: two case reports with an overdose of propranolol.婴儿血管瘤:两例普萘洛尔过量病例报告
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引用本文的文献

1
Excessively High Chronic Propranolol Overdose in Infantile Hemangioma: A Case Report.婴儿血管瘤中超剂量慢性普萘洛尔用药:病例报告。
Am J Case Rep. 2023 Nov 27;24:e941765. doi: 10.12659/AJCR.941765.
2
Propranolol in use for treatment of complex infant hemangiomas: literature review regarding current guidelines for preassessment and standards of care before initiation of therapy.普萘洛尔用于治疗复杂型婴儿血管瘤:关于治疗开始前预评估现行指南及护理标准的文献综述
ScientificWorldJournal. 2013 May 20;2013:850193. doi: 10.1155/2013/850193. Print 2013.

本文引用的文献

1
Scoring the proliferative activity of haemangioma of infancy: the Haemangioma Activity Score (HAS).评估婴儿血管瘤的增殖活性:血管瘤活动评分(HAS)。
Clin Exp Dermatol. 2011 Oct;36(7):715-23. doi: 10.1111/j.1365-2230.2011.04080.x. Epub 2011 Jun 10.
2
Hypoglycemia in children taking propranolol for the treatment of infantile hemangioma.服用普萘洛尔治疗婴儿血管瘤的儿童发生低血糖症。
Arch Dermatol. 2010 Jul;146(7):775-8. doi: 10.1001/archdermatol.2010.158.
3
Propranolol for complicated infantile haemangiomas: a case series of 30 infants.
普萘洛尔治疗复杂型婴儿血管瘤:30例婴儿病例系列
Br J Dermatol. 2010 Feb 1;162(2):466-8. doi: 10.1111/j.1365-2133.2009.09597.x. Epub 2010 Jan 6.
4
Propranolol treatment for hemangioma of infancy: risks and recommendations.普萘洛尔治疗婴幼儿血管瘤:风险与建议
Pediatr Dermatol. 2009 Sep-Oct;26(5):610-4. doi: 10.1111/j.1525-1470.2009.00975.x.
5
Propranolol for severe infantile hemangiomas: follow-up report.普萘洛尔治疗严重婴幼儿血管瘤:随访报告。
Pediatrics. 2009 Sep;124(3):e423-31. doi: 10.1542/peds.2008-3458. Epub 2009 Aug 10.