A prospective clinical pilot-trial comparing the effect of an optimized mixed diet versus a flexible low-glycemic index diet on nutrient intake and HbA(1c) levels in children with type 1 diabetes.
作者信息
Marquard Jan, Stahl Anna, Lerch Christian, Wolters Mareen, Grotzke-Leweling Maike, Mayatepek Ertan, Meissner Thomas
机构信息
Department of General Pediatrics, University Children's Hospital Duesseldorf, Duesseldorf, Germany.
出版信息
J Pediatr Endocrinol Metab. 2011;24(7-8):441-7. doi: 10.1515/jpem.2011.176.
BACKGROUND
Low-glycemic index (GI) diet vs. high-GI diet improves glycemic control, but it is not clear whether a low-GI diet is superior to an optimized mixed diet (OMD).
METHODS
This was a 12-week parallel-group pilot-trial including 17 children with type 1 diabetes. A separate dietary education into the allocated diet (OMD vs. low-GI) was performed. Nutrition was recorded by means of a three-day dietary record.
OBJECTIVES
The primary objective was to determine the macro- and micronutrient composition of the different diets, the secondary objective was to determine the short-term effect on HbA(1c) levels.
RESULTS
In the low-GI group carbohydrate intake decreased, fat intake increased by trend. In the OMD group fat and energy intake decreased. No changes of HbA(1c) levels between the groups were observed.
CONCLUSION
OMD could have positive effects in overweight and obese diabetic children, since a reduction in fat and energy intake can be achieved. The findings of this pilot-trial suggest that OMD could be superior to a low-GI diet.
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