Reece E A, Assimakopoulos E, Zheng X Z, Hagay Z, Hobbins J C
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut.
Obstet Gynecol. 1990 Jul;76(1):139-46.
It has been estimated that more than half of all pregnant women in the United States undergo diagnostic ultrasound during their pregnancies. In light of this, the question of safety is of fundamental importance. Nondiagnostic ultrasound has been shown to produce biologic effects by thermal and cavitational activities. However, diagnostic ultrasound uses much lower intensities, and no evidence exists to suggest that it is associated with adverse effects. Numerous studies have examined the biologic effects of diagnostic ultrasound in insects, plants, cell suspensions, and even small mammals. The data from these experiments are confusing when attempting to relate these findings to the human. Epidemiologic data in humans, used to evaluate the potential adverse effects of exposure to diagnostic ultrasound, have revealed no ill effects from such exposure. Current data indicate that there are no confirmed biologic effects on patients and their fetuses from the use of diagnostic ultrasound and that the benefits to patients exposed to prudent use of diagnostic ultrasound outweigh the risks, if any. This review discusses the available information on the safety of obstetric ultrasonography.
据估计,美国超过半数的孕妇在孕期接受诊断性超声检查。鉴于此,安全性问题至关重要。已表明非诊断性超声通过热效应和空化作用产生生物学效应。然而,诊断性超声使用的强度要低得多,且没有证据表明其与不良反应有关。众多研究已在昆虫、植物、细胞悬液甚至小型哺乳动物中研究了诊断性超声的生物学效应。当试图将这些研究结果与人类联系起来时,这些实验的数据令人困惑。用于评估诊断性超声暴露潜在不良反应的人类流行病学数据显示,此类暴露没有不良影响。目前的数据表明,使用诊断性超声对患者及其胎儿没有确凿的生物学效应,并且谨慎使用诊断性超声给患者带来的益处超过了任何潜在风险。本综述讨论了有关产科超声检查安全性的现有信息。