[2006 - 2008年北京急性弛缓性麻痹和手足口病患病率研究]
[Study on the prevalence of acute flaccid paralysis and hand foot mouth disease in Beijing 2006 - 2008].
作者信息
Luo Ming, Gong Cheng, Zhang Tie-gang, Zhang Zhu-jia-zi
机构信息
Beijing Center for Disease Control and Prevention, Beijing 100013, China.
出版信息
Zhonghua Liu Xing Bing Xue Za Zhi. 2011 Jul;32(7):681-4.
OBJECTIVE
To study the prevalence of acute flaccid paralysis (AFP) and hand foot mouth disease (HFMD) in Beijing, from 2006 - 2008.
METHODS
Data on AFP and HFMD was analyzed epidemiologically, during 2006 - 2008 in Beijing. All the specimens from AFP cases were isolated and identified by RD and L20B cell and all of non-polio enterovirus (NPEV) cases were assayed by HFMD real-time PCR kit. The relationship between AFP and HFMD was analyzed.
RESULTS
During 2006 - 2008, the number of AFP case in Beijing increased from 108 to 177 while the NPEV isolation rate increased from 11.11% to 20.34% and the positive rate of enterovirus 71 (EV71) and/or coxsackie virus A16 (Cox A16) increased from 0.93% to 10.17%.
CONCLUSION
The prevalence of HFMD caused by EV71 and/or Cox A16 might have contributed to the increase of AFP cases in Beijing.
目的
研究2006 - 2008年北京市急性弛缓性麻痹（AFP）和手足口病（HFMD）的流行情况。
方法
对2006 - 2008年北京市AFP和HFMD数据进行流行病学分析。所有AFP病例标本采用RD和L20B细胞进行分离鉴定，所有非脊髓灰质炎肠道病毒（NPEV）病例采用手足口病实时荧光定量PCR试剂盒检测。分析AFP与HFMD之间的关系。
结果
2006 - 2008年，北京市AFP病例数从108例增加到177例，NPEV分离率从11.11%提高到20.34%，肠道病毒71型（EV71）和/或柯萨奇病毒A16型（Cox A16）阳性率从0.93%提高到10.17%。
结论
由EV71和/或Cox A16引起的手足口病流行可能是导致北京市AFP病例数增加的原因。
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