Navratil Marta, Pavić Ivan, Paštar Zrinjka, Caleta Drago
Srebrnjak Children’s Hospital, School of Medicine University of Zagreb, Croatia.
Acta Dermatovenerol Croat. 2011;19(3):176-9.
We report a case of a 17-year-old female adolescent who experienced an episode of exercise-induced anaphylactic reaction following ingestion of tuna sandwich (from soy containing canned tuna). Her medical history revealed that she had previously had one episode of urticaria after ingestion of sulfamethoxazole with trimethoprim and anaphylactic reaction after ingestion of sunflower nuts. Skin prick tests and specific immunoglobulin E antibody to tuna were negative, and to soy were positive. Treadmill exercise induced test in fasting state and 1 hour after a fresh tuna meal and meal not containing soy were negative. However, an exercise challenge test one hour after soy ingestion resulted in pruritus of hands, shoulders and back, urticarial lesions of the face and neck with angioedema of the lips and eyelids, hoarseness, tachycardia and anxiety.
我们报告一例17岁女性青少年病例，该患者在食用金枪鱼三明治（来自含大豆的罐装金枪鱼）后出现了运动诱发的过敏反应。她的病史显示，她之前在服用磺胺甲恶唑与甲氧苄啶后曾有一次荨麻疹发作，在食用葵花籽后出现过敏反应。皮肤点刺试验及针对金枪鱼的特异性免疫球蛋白E抗体检测为阴性，而针对大豆的检测为阳性。空腹状态下以及食用新鲜金枪鱼餐和不含大豆的餐食1小时后的跑步机运动诱发试验均为阴性。然而，在摄入大豆1小时后的运动激发试验导致手部、肩部和背部瘙痒，面部和颈部出现荨麻疹皮损，伴有嘴唇和眼睑血管性水肿、声音嘶哑、心动过速和焦虑。
