Lin H Y, Shyur S D, Fu J L, Lai Y C, Lin J S
Department of Pediatrics and Medical Research, Mackay Memorial Hospital, Taipei, Taiwan, R.O.C.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1998 May-Jun;39(3):200-2.
In the past 2 years, a 4 year-old boy has had an anaphylactic reaction whenever he contacted food prepared with fish. The symptoms included intense itching in the throat and eyes, which progressed to generalized urticaria and facial angioedema. This was accompanied by cough, wheezing and dyspnea. Many fish preparations caused these episodes including several different kinds of fish (cod, tuna, salmon, trout, eel...), fish soup, chopsticks contaminated with fish preparations and canned fish. Elevated levels of total serum IgE (224 IU/ml) and specific IgE for cod (93.1 IU/ml), tuna (> 100 IU/ml), salmon (> 100 IU/ml), trout (64.4 IU/ml), mackerel (41.2 IU/ml) and eel (28.1 IU/ml) were found by the Pharmacia CAP system RAST FEIA in our allergy clinic. A skin prick test for mixed fish extracts (contain flounder, cod and halibut) was positive. A fish challenge test for cod, tuna, salmon, trout and eel all showed anaphylactic reactions. His allergic symptoms stabilized gradually after strictly avoiding ingestion of fish and using drug treatment. He also had a similar anaphylactic reaction to frogs. The best treatment for fish allergy is avoidance. Avoidance of fish may need to include both ingestion and inhalation of cooking vapors.
在过去两年里，一名4岁男孩每当接触用鱼制作的食物时都会发生过敏反应。症状包括喉咙和眼睛剧烈瘙痒，进而发展为全身性荨麻疹和面部血管性水肿。同时伴有咳嗽、喘息和呼吸困难。许多鱼制品都会引发这些症状，包括几种不同的鱼（鳕鱼、金枪鱼、鲑鱼、鳟鱼、鳗鱼……）、鱼汤、被鱼制品污染的筷子以及罐装鱼。在我们的过敏诊所，通过Pharmacia CAP系统RAST FEIA检测发现，总血清IgE水平升高（224 IU/ml），以及针对鳕鱼（93.1 IU/ml）、金枪鱼（>100 IU/ml）、鲑鱼（>100 IU/ml）、鳟鱼（64.4 IU/ml）、鲭鱼（41.2 IU/ml）和鳗鱼（28.1 IU/ml）的特异性IgE升高。对混合鱼提取物（包含比目鱼、鳕鱼和大比目鱼）进行的皮肤点刺试验呈阳性。对鳕鱼、金枪鱼、鲑鱼、鳟鱼和鳗鱼进行的鱼类激发试验均显示出过敏反应。在严格避免摄入鱼类并进行药物治疗后，他的过敏症状逐渐稳定。他对青蛙也有类似的过敏反应。鱼类过敏的最佳治疗方法是避免接触。避免接触鱼类可能需要同时避免摄入以及吸入烹饪时产生的蒸汽。
