Siekierka-Harreis M, Rump L C
Klinik für Nephrologie, Heinrich-Heine Universität Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Deutschland.
Internist (Berl). 2011 Oct;52(10):1167-77. doi: 10.1007/s00108-011-2824-5.
The prevalence of chronic kidney disease in women of childbearing age reaches approximately 0.2%. Under physiological conditions pregnancy results in important hemodynamic changes on the maternal organism. In the case of chronic kidney disease these adaptations often are only partial. Physiological changes of immune response during pregnancy may contribute to the progress of renal disease. Regardless of the underlying kidney disease, one can assume that the better the glomerular filtration rate and blood pressure are the more favorable the course of pregnancy will be with the chance for a healthy child and stable renal function. To achieve this goal, a close interaction is required between gynecologist, nephrologist, and other specialists in a center with appropriate experience.
育龄期女性慢性肾脏病的患病率约为0.2%。在生理条件下,妊娠会导致母体机体发生重要的血流动力学变化。对于慢性肾脏病患者,这些适应性变化往往只是部分性的。妊娠期间免疫反应的生理变化可能会促使肾脏疾病进展。无论潜在的肾脏疾病如何,都可以认为肾小球滤过率和血压越好,妊娠过程就越有利,生出健康婴儿且肾功能稳定的机会就越大。为实现这一目标,妇科医生、肾病科医生和其他有适当经验的专科医生在一个中心需要密切协作。