Department of Neurosurgery, Kansai Medical University, Moriguchi, Japan.
Brain Tumor Pathol. 2012 Jan;29(1):63-7. doi: 10.1007/s10014-011-0056-y. Epub 2011 Sep 21.
The patient was a 72-year-old woman who had previously undergone treatment for femoral chondrosarcoma (histologically rated as myxofibrosarcoma). She suddenly developed left homonymous hemianopsia and was diagnosed with cerebral embolism. Because she had atrial fibrillation, we treated her for cardiogenic cerebral embolism. About 3 months later, however, she developed left hemiplegia, and head magnetic resonance imaging revealed multiple tumorous lesions affecting the previously detected infracted area and several new areas. We assumed that a tumor embolus had caused cerebral embolism, which resulted in growth of the tumor from the embolus and formation of a metastatic brain tumor. The metastatic foci formed from the tumor embolus were visualized by diagnostic imaging, and histological examination of the resected tumor confirmed that the brain tumor had occluded the brain vessel (tumorigenic cerebral embolism). No such case has been reported to date, and this case seems to be important.
患者为 72 岁女性，曾因股骨软骨肉瘤（组织学分级为黏液纤维肉瘤）接受治疗。她突然出现左侧同向性偏盲，并被诊断为脑栓塞。由于她有心房颤动，我们对其进行了心源性脑栓塞的治疗。然而，大约 3 个月后，她出现左侧偏瘫，头部磁共振成像显示多个肿瘤性病变影响之前检测到的梗死区域和几个新区域。我们假设肿瘤栓子引起了脑栓塞，导致栓子处的肿瘤生长并形成转移性脑肿瘤。诊断性影像学检查显示肿瘤栓子形成的转移灶，切除肿瘤的组织学检查证实脑肿瘤阻塞了脑血管（肿瘤性脑栓塞）。迄今为止尚未报告此类病例，该病例似乎很重要。
