Shao Lei, Willard M J, Lowe Lisa H, Singh Vivekanand
Department of Pathology, Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64104, USA.
Pediatr Dev Pathol. 2008 Mar-Apr;11(2):156-9. doi: 10.2350/07-02-0241.1. Epub 2007 Jun 7.
Fatal embolic chondroblastic osteosarcoma to the lung is an extremely rare phenomenon. We report a case of a 15-year-old boy who developed bilateral pulmonary embolism shortly after resection of the right distal femur for chondroblastic osteosarcoma. The patient succumbed to right-sided heart failure 8 weeks later. An autopsy revealed extensive intravascular tumor emboli in the bilateral pulmonary arteries and their branches. No metastatic lesions were identified in the lungs. We review the clinical, radiologic, and pathologic findings of this patient and the literature.
致命性肺栓塞性软骨母细胞性骨肉瘤是一种极为罕见的现象。我们报告一例15岁男孩,其在因软骨母细胞性骨肉瘤行右股骨远端切除术后不久发生双侧肺栓塞。患者在8周后死于右侧心力衰竭。尸检显示双侧肺动脉及其分支内有广泛的血管内肿瘤栓子。肺部未发现转移灶。我们回顾了该患者的临床、影像学和病理学表现以及相关文献。