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[应用膀胱内灌注白矾治疗环磷酰胺所致出血性膀胱炎。附5例报告]

[Treatment of hemorrhagic cystitis caused by cyclophosphamide using intravesical instillation of potassium alum. Apropos of 5 cases].

作者信息

Gattegno B, Guillemenot F, Fiatte P, Cohen L, Becker A, Gluckman E, Thibault P

机构信息

Clinique Urologique, Hôpital Tenon, Paris.

出版信息

Ann Urol (Paris). 1990;24(3):190-2.

PMID:2193606
Abstract

Five patients with malignant hemopathies, including four treated by bone marrow transplantation, developed cyclophosphamide-induced hemorrhagic cystitis that failed to respond to the usual treatments. Each was treated by continuous irrigation of the bladder with potassium alum. Hematuria ceased in three patients followed up for 5 to 10 months. A review of the literature confirmed the 75% success rate of this treatment. No local side effects were recorded, but one patient had a single seizure.

摘要

5例恶性血液病患者,其中4例接受了骨髓移植治疗,发生了环磷酰胺诱导的出血性膀胱炎,常规治疗无效。每例患者均采用明矾钾持续膀胱冲洗治疗。3例随访5至10个月的患者血尿停止。文献回顾证实了该治疗75%的成功率。未记录到局部副作用,但有1例患者发生了1次癫痫发作。

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