Kashida Hiroshi, Ikehara Nobunao, Hamatani Shigeharu, Kudo Shin-ei, Kudo Masatoshi
Showa University, Northern Yokohama Hospital, Yokohama, Japan.
Hepatogastroenterology. 2011 Jul-Aug;58(109):1163-7. doi: 10.5754/hge10093.
BACKGROUND/AIMS: With the recent changes of pathological concepts, colorectal serrated lesions can be now divided into traditional serrated adenoma, typical hyperplastic polyp and sessile serrated polyp. The aim of this study is to clarify the endoscopic differences among these three groups.
A total number of 362 serrated lesions larger than 5mm were evaluated. These were detected with ordinary view and observed also with magnifying chromoendoscopic view. The final pathologic diagnosis of the resected specimens was made blinded.
There were significant differences between traditional serrated adenoma and sessile serrated polypconcerning location, configuration and color. In chromoendoscopy, most of sessile serrated polyps and typical hyperplastic polyps showed star-like pattern, in contrast with traditional serrated adenomas most of which had fernor pinecone-like pattern. The differential diagnosis between traditional sessile polyp and the other two was possible with high accuracy. On the other hand, endoscopic distinction between sessile serrated polyp and typical hyperplastic polyp was not easy, except that the location and size were significantly different.
We can endoscopically differentiate between traditional serrated adenoma and sessile serrated polyp or typical hyperplastic polyp, but it is difficult to differentiate between the latter two.
背景/目的:随着病理概念的最新变化,结直肠锯齿状病变现在可分为传统锯齿状腺瘤、典型增生性息肉和无蒂锯齿状息肉。本研究的目的是阐明这三组病变在内镜下的差异。
对362个直径大于5mm的锯齿状病变进行评估。这些病变通过普通视野检测,并同时用放大染色内镜视野观察。对切除标本的最终病理诊断是在不知情的情况下做出的。
传统锯齿状腺瘤与无蒂锯齿状息肉在位置、形态和颜色方面存在显著差异。在染色内镜检查中,大多数无蒂锯齿状息肉和典型增生性息肉呈现星状形态,而大多数传统锯齿状腺瘤呈现蕨类或松果状形态。传统无蒂息肉与其他两者之间的鉴别诊断具有较高的准确性。另一方面,除了位置和大小存在显著差异外,无蒂锯齿状息肉与典型增生性息肉之间的内镜鉴别并不容易。
我们可以通过内镜鉴别传统锯齿状腺瘤与无蒂锯齿状息肉或典型增生性息肉,但鉴别后两者较为困难。