Department of Neuroradiology, Charité Universitary Medicine, Abt. Neuroradiologie, Charitéplatz 1, 10117 Berlin, Germany.
Neurol Sci. 2012 Aug;33(4):741-7. doi: 10.1007/s10072-011-0785-z. Epub 2011 Sep 22.
The objective of the study was to use 320-detector row 4D CT angiography (CTA) for measuring cerebral circulation times (CCT) and to assess early venous drainage (EVD) and shortening of CCT in arteriovenous malformations (AVM) and to compare with DSA. CCT of 12 physiological patients and five AVM patients were acquired using a 4D CTA protocol by recording cerebrovascular bolus passage time. In the AVM patients EVD time (EVDT) was measured. Identical measurements were performed on DSA for the AVM patients. It was found that the physiological CCTs were 5.8 ± 1.4 s (M ± SD). EVD was seen in all AVMs and resulted in a shortened CCT of 3.4 ± 1.1 s (p = 0.01). There was no significant difference for CCT and EVDT values derived from DSA and 4D CTA. Thus, the CCTs can be measured non-invasively using clinical 4D CTA. Early venous drainage with shortened CCTs was observed by 4D CTA in all five patients with AVMs.
本研究旨在利用 320 排 4D CT 血管造影（CTA）测量脑循环时间（CCT），评估动静脉畸形（AVM）中的早期静脉引流（EVD）和 CCT 缩短情况，并与 DSA 进行比较。通过记录脑血管造影剂通过时间，使用 4D CTA 方案获取 12 例生理患者和 5 例 AVM 患者的 CCT。在 AVM 患者中测量 EVD 时间（EVDT）。对 AVM 患者的 DSA 进行相同的测量。结果发现，生理 CCT 为 5.8±1.4s（M±SD）。所有 AVM 均可见 EVD，导致 CCT 缩短 3.4±1.1s（p=0.01）。DSA 和 4D CTA 得出的 CCT 和 EVDT 值无显著差异。因此，使用临床 4D CTA 可以无创测量 CCT。通过 4D CTA 在所有 5 例 AVM 患者中观察到 CCT 缩短的早期静脉引流。
