Moltó José, Miranda Cristina, Malo Sara, Valle Marta, Andreu Angels, Bonafont Xavier, Clotet Bonaventura
Fundació Lluita contra la Sida, Hospital de día de VIH, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, España.
Med Clin (Barc). 2012 Feb 18;138(3):93-8. doi: 10.1016/j.medcli.2011.04.031. Epub 2011 Sep 21.
To evaluate the prevalence and patterns of use of herbal remedies among HIV-infected patients, and to identify potential health risks and correlates associated with the use of these products.
Cross-sectional survey including 1000 HIV-infected outpatients in Barcelona. Participants completed a questionnaire on the use of herbal remedies and other types of complementary treatments within the previous year as well as on sociodemographic and clinical characteristics. Herbal users' questionnaires were scrutinized for potential adverse effects and drug interactions with antiretroviral treatment. Correlates of use of herbal remedies were evaluated through logistic regression analyses.
One third of patients (n=355) had used herbal remedies, but doctors were informed about such a use by only 69 (19.4%) herbal users. Potential health problems were identified in 193 (54.4%) cases. Herbal remedy use was related to a history of ever discussing complementary and alternative medicine use with the physician (OR: 3.12; 95% CI: 2.30-4.23), having a secondary-school or higher education (OR: 2.63; 95% CI: 1.78-3.88), and perception of complementary therapies as effective (OR: 2.28; 95% CI: 1.18-4.41). Other factors were non-Caucasian ethnicity (OR: 1.65; 95% CI: 1.07-2.56) and the presence of non-HIV-related symptoms (OR: 1.68; 95% CI: 1.24-2.28).
Herbal remedy use is common among HIV-infected patients. HIV caregivers and patients should be sensitized to potential risks and the use of these remedies should be routinely monitored in clinical practice.
评估HIV感染患者中草药疗法的使用流行情况及模式，并识别与使用这些产品相关的潜在健康风险及关联因素。
对巴塞罗那1000名HIV感染门诊患者进行横断面调查。参与者完成一份关于前一年使用草药疗法及其他类型补充疗法的问卷，以及关于社会人口学和临床特征的问卷。仔细检查草药使用者的问卷，以寻找潜在不良反应及与抗逆转录病毒治疗的药物相互作用。通过逻辑回归分析评估草药疗法使用的关联因素。
三分之一的患者（n = 355）使用过草药疗法，但只有69名（19.4%）草药使用者告知了医生这种使用情况。193例（54.4%）发现有潜在健康问题。草药疗法的使用与曾与医生讨论补充和替代医学使用的病史（比值比：3.12；95%可信区间：2.30 - 4.23）、接受过中学或更高教育（比值比：2.63；95%可信区间：1.78 - 3.88）以及认为补充疗法有效（比值比：2.28；95%可信区间：1.18 - 4.41）有关。其他因素包括非白种人种族（比值比：1.65；95%可信区间：1.07 - 2.56）和存在非HIV相关症状（比值比：1.68；95%可信区间：1.24 - 2.28）。
草药疗法在HIV感染患者中使用普遍。HIV护理人员和患者应提高对潜在风险的认识，在临床实践中应常规监测这些疗法的使用情况。
