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本文引用的文献

1
Characterization and correction of beam-hardening artifacts during dynamic volume CT assessment of myocardial perfusion.动态容积 CT 评估心肌灌注期间的射束硬化伪影的特征与校正。
Radiology. 2010 Jul;256(1):111-8. doi: 10.1148/radiol.10091399.
2
A method for reconstructing the arterial input function during helical CT: implications for myocardial perfusion distribution imaging.一种在螺旋 CT 中重建动脉输入函数的方法：对心肌灌注分布成像的影响。
Radiology. 2010 May;255(2):396-404. doi: 10.1148/radiol.10081121. Epub 2010 Mar 23.
3
Meta-analysis: noninvasive coronary angiography using computed tomography versus magnetic resonance imaging.荟萃分析：计算机断层扫描与磁共振成像用于非侵入性冠状动脉造影。
Ann Intern Med. 2010 Feb 2;152(3):167-77. doi: 10.7326/0003-4819-152-3-201002020-00008.
4
Patient characteristics as predictors of image quality and diagnostic accuracy of MDCT compared with conventional coronary angiography for detecting coronary artery stenoses: CORE-64 Multicenter International Trial.患者特征作为 MDCT 与常规冠状动脉造影检测冠状动脉狭窄的图像质量和诊断准确性的预测因素：CORE-64 多中心国际试验。
AJR Am J Roentgenol. 2010 Jan;194(1):93-102. doi: 10.2214/AJR.09.2833.
5
Adenosine stress 64- and 256-row detector computed tomography angiography and perfusion imaging: a pilot study evaluating the transmural extent of perfusion abnormalities to predict atherosclerosis causing myocardial ischemia.腺苷负荷64排和256排探测器计算机断层血管造影及灌注成像：一项评估灌注异常透壁范围以预测引起心肌缺血的动脉粥样硬化的初步研究。
Circ Cardiovasc Imaging. 2009 May;2(3):174-82. doi: 10.1161/CIRCIMAGING.108.813766. Epub 2009 Mar 31.
6
Adenosine-induced stress myocardial perfusion imaging using dual-source cardiac computed tomography.使用双源心脏计算机断层扫描的腺苷诱导应激心肌灌注成像
J Am Coll Cardiol. 2009 Sep 15;54(12):1072-84. doi: 10.1016/j.jacc.2009.06.014.
7
Noninvasive coronary angiography by 320-row computed tomography with lower radiation exposure and maintained diagnostic accuracy: comparison of results with cardiac catheterization in a head-to-head pilot investigation.320排计算机断层扫描进行的低辐射暴露且诊断准确性得以维持的无创冠状动脉造影：在一项直接比较的初步研究中与心脏导管插入术的结果对比
Circulation. 2009 Sep 8;120(10):867-75. doi: 10.1161/CIRCULATIONAHA.109.859280. Epub 2009 Aug 24.
8
Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study.64层计算机断层扫描冠状动脉造影的诊断准确性：一项前瞻性、多中心、多厂家研究。
J Am Coll Cardiol. 2008 Dec 16;52(25):2135-44. doi: 10.1016/j.jacc.2008.08.058.
9
Diagnostic performance of coronary angiography by 64-row CT.64排CT冠状动脉造影的诊断性能
N Engl J Med. 2008 Nov 27;359(22):2324-36. doi: 10.1056/NEJMoa0806576.
10
Diagnostic performance of 64-multidetector row coronary computed tomographic angiography for evaluation of coronary artery stenosis in individuals without known coronary artery disease: results from the prospective multicenter ACCURACY (Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive Coronary Angiography) trial.64排冠状动脉计算机断层扫描血管造影术对无已知冠状动脉疾病个体冠状动脉狭窄评估的诊断性能：前瞻性多中心ACCURACY（冠状动脉计算机断层扫描血管造影术对接受有创冠状动脉造影术个体的评估）试验结果
J Am Coll Cardiol. 2008 Nov 18;52(21):1724-32. doi: 10.1016/j.jacc.2008.07.031.

采用 320 排 MDCT 进行无创性冠状动脉血管造影和心肌灌注成像的诊断性能：COrE320 多中心多国诊断研究的 CT 血管造影和灌注方法。

Diagnostic performance of combined noninvasive coronary angiography and myocardial perfusion imaging using 320-MDCT: the CT angiography and perfusion methods of the CORE320 multicenter multinational diagnostic study.

机构信息

Department of Medicine, Division of Cardiology, Johns Hopkins University School Medicine, 600 N Wolfe St, Carnegie Bldg 565C, Baltimore, MD 21287, USA.

出版信息

AJR Am J Roentgenol. 2011 Oct;197(4):829-37. doi: 10.2214/AJR.10.5689.

DOI:10.2214/AJR.10.5689
PMID:21940569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3302727/
Abstract

OBJECTIVE

Coronary MDCT angiography has been shown to be an accurate noninvasive tool for the diagnosis of obstructive coronary artery disease (CAD). Its sensitivity and negative predictive value for diagnosing percentage of stenosis are unsurpassed compared with those of other noninvasive testing methods. However, in its current form, it provides no information regarding the physiologic impact of CAD and is a poor predictor of myocardial ischemia. CORE320 is a multicenter multinational diagnostic study with the primary objective to evaluate the diagnostic accuracy of 320-MDCT for detecting coronary artery luminal stenosis and corresponding myocardial perfusion deficits in patients with suspected CAD compared with the reference standard of conventional coronary angiography and SPECT myocardial perfusion imaging.

CONCLUSION

We aim to describe the CT acquisition, reconstruction, and analysis methods of the CORE320 study.

摘要

目的

冠状动脉 MDCT 血管造影术已被证明是一种用于诊断阻塞性冠状动脉疾病（CAD）的准确的非侵入性工具。与其他非侵入性检查方法相比，其在诊断狭窄程度百分比方面的敏感性和阴性预测值是无与伦比的。然而，在其当前形式下，它没有提供关于 CAD 的生理影响的信息，并且是心肌缺血的不良预测因子。CORE320 是一项多中心、多国的诊断研究，其主要目的是评估 320-MDCT 在检测疑似 CAD 患者的冠状动脉管腔狭窄和相应心肌灌注缺陷方面的诊断准确性，与常规冠状动脉造影和 SPECT 心肌灌注成像的参考标准进行比较。

结论

我们旨在描述 CORE320 研究的 CT 采集、重建和分析方法。