Ng Danny S, Wong Ian Y, Chan Clement W
Department of Ophthalmology, Tung Wah Eastern Hospital, University of Hong Kong, Hong Kong, SAR, China.
Case Rep Ophthalmol. 2011 May;2(2):266-72. doi: 10.1159/000331202. Epub 2011 Aug 18.
During a 6-month period in 2010, 2 patients with uveitis were examined at our department and diagnosed with ocular syphilis. They initially presented with symptoms and signs resembling Harada's disease and Behçet's disease and were therefore treated with systemic steroids with suboptimal responses. When laboratory workup revealed neurosyphilis, they were given a course of intravenous penicillin G, which led to significant clinical and visual improvement. Epidemiological data indicates a worldwide reemergence of syphilis and a high degree of suspicion is necessary in view of its multitude of presenting ocular signs without pathognomonic features.
在2010年的6个月期间,我们科室检查了2例葡萄膜炎患者,诊断为眼梅毒。他们最初表现出类似于原田病和白塞病的症状和体征,因此接受了全身类固醇治疗,但反应欠佳。当实验室检查发现神经梅毒时,他们接受了一个疗程的静脉注射青霉素G治疗,这导致了显著的临床和视力改善。流行病学数据表明梅毒在全球再度出现,鉴于其众多无特征性表现的眼部体征,高度怀疑很有必要。