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乳腺原发性粒细胞肉瘤:一例报告并文献复习

Primary granulocytic sarcoma of the breast: a case report and review of the literature.

作者信息

Delporte F, Voorhoopf L J B, Lodewyck T, De Paepe P

机构信息

Department of Obstetrics and Gynaecology, Sint-Jan Hospital Bruges, Ghent, Belgium.

出版信息

Eur J Gynaecol Oncol. 2011;32(4):435-8.

Abstract

Primary granulocytic sarcoma is an uncommon entity that rarely presents in the breast. It is frequently misdiagnosed as carcinoma or lymphoma and a broad panel of immunohistochemical markers including epithelial and haematological markers are essential for an accurate diagnosis. We reviewed all the cases of granulocytic sarcoma reported in the English literature since 1970 and present a new case of granulocytic sarcoma of the breast. Systemic chemotherapy for acute myeloid leukemia (AML) appears to be superior to surgery or radiotherapy. Granulocytic sarcoma should be in the pathologic differential diagnosis of a breast mass.

摘要

原发性粒细胞肉瘤是一种罕见的疾病,很少出现在乳腺中。它常被误诊为癌或淋巴瘤,一系列广泛的免疫组化标志物,包括上皮和血液学标志物,对于准确诊断至关重要。我们回顾了自1970年以来英文文献中报道的所有粒细胞肉瘤病例,并展示了一例新的乳腺粒细胞肉瘤病例。急性髓系白血病(AML)的全身化疗似乎优于手术或放疗。粒细胞肉瘤应列入乳腺肿块的病理鉴别诊断。

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