原发性喉粒细胞肉瘤
Primary granulocytic sarcoma of larynx.
作者信息
Kim Luke Y, Purkey Michael T, Patel Mihir R, Ghosh Ankona, Hartner Lee, Newman Jason G
机构信息
Department of Otorhinolaryngology - Head and Neck Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
出版信息
Head Neck. 2015 Mar;37(3):E38-44. doi: 10.1002/hed.23805. Epub 2014 Nov 13.
BACKGROUND
Granulocytic sarcoma is an extramedullary tumor of myeloblasts. The purpose of this report was to present a case of a primary laryngeal granulocytic sarcoma and review of the literature.
METHODS
A literature review was performed using Medline and PubMed databases to search for cases of all primary and secondary myelogenous tumors of the larynx.
RESULTS
A 36-year-old man presented with a mass involving the preepiglottic space that was histologically confirmed as an extramedullary acute myeloid leukemia, or granulocytic sarcoma. Our review found 18 cases of secondary involvement of the larynx by myelogenous tumors, and only 1 previously reported case of primary laryngeal granulocytic sarcoma.
CONCLUSION
The detection of granulocytic sarcoma is difficult given its rarity and nonspecific presentation. To our knowledge, this is the second reported case of primary granulocytic sarcoma of the larynx reported in the literature.
背景
粒细胞肉瘤是一种成髓细胞的髓外肿瘤。本报告的目的是呈现一例原发性喉粒细胞肉瘤病例并进行文献复习。
方法
使用Medline和PubMed数据库进行文献复习，以搜索所有原发性和继发性喉髓性肿瘤的病例。
结果
一名36岁男性出现累及会厌前间隙的肿块，组织学证实为髓外急性髓细胞白血病，即粒细胞肉瘤。我们的复习发现18例髓性肿瘤继发性累及喉的病例，仅有1例先前报道的原发性喉粒细胞肉瘤病例。
结论
鉴于粒细胞肉瘤罕见且表现不具特异性，其检测较为困难。据我们所知，这是文献中报道的第二例原发性喉粒细胞肉瘤病例。
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