Westerhoff Hans V
Manchester Centre for Integrative Systems Biology, The University of Manchester, Manchester, United Kingdom.
Methods Enzymol. 2011;500:3-11. doi: 10.1016/B978-0-12-385118-5.00001-3.
Systems biology has come of age. In most scientifically active countries, significant research programs are funded. Various scientific journals, standards, repositories, and Web sites are devoted to the topic. Systems biology has spun off new subdisciplines such as synthetic biology and systems medicine. There are training courses at the M.Sc. and Ph.D. level at various Universities. And various industries are engaging systems biology in their R&D. Systems biology has also developed numerous new methodologies. This chapter attempts to organize these methodologies from the perspectives of the unique aims of systems biology, and by comparing with one of its parents, molecular biology.
系统生物学已经成熟。在大多数科研活跃的国家，都有重要的研究项目获得资助。各种科学期刊、标准、资料库和网站都致力于该主题。系统生物学衍生出了新的子学科，如合成生物学和系统医学。在多所大学有硕士和博士水平的培训课程。而且各个行业都在其研发中运用系统生物学。系统生物学还开发了众多新方法。本章试图从系统生物学的独特目标角度，并通过与它的母体学科之一分子生物学进行比较，来梳理这些方法。
