Department of Urology, Paracelsus Medical University Salzburg, Salzburg, Austria.
J Urol. 2011 Nov;186(5):1967-71. doi: 10.1016/j.juro.2011.07.026. Epub 2011 Sep 23.
We ascertained the safety and efficacy of the 1,318 nm diode Eraser laser (Rolle and Rolle, Salzburg, Austria) for transurethral enucleation of the prostate. This laser has been successfully used to resect lung metastasis. It cuts and coagulates vascular rich tissue safely and effectively. We describe a prospective, randomized trial of Eraser laser prostate enucleation vs bipolar transurethral prostate resection.
A total of 60 patients with lower urinary tract symptoms suggesting bladder outlet obstruction and a mean prostate size of 59.5 ml on transrectal ultrasound were randomized to Eraser laser prostate enucleation or bipolar transurethral prostate resection. Patients were assessed preoperatively, and 1 and 6 months postoperatively.
Eraser laser prostate enucleation was equivalent to bipolar transurethral prostate resection in improvement in International Prostate Symptom Score, maximal flow rate and quality of life. Laser enucleation was significantly superior to bipolar transurethral resection for measured blood loss (mean ± SD 116.83 ± 97.02 vs 409.83 ± 148.61 ml), catheter time (mean 32.80 ± 8.74 vs 65.73 ± 13.72 hours) and hospital time (mean 45.13 ± 14.77 vs 91.20 ± 11.76 hours, each p <0.05). Using the validated Clavien-Dindo system there were 3 grade Id and 1 grade II complications.
Eraser laser prostate enucleation and bipolar transurethral prostate resection were equally safe and effective to relieve bladder outflow obstruction and lower urinary tract symptoms. This laser technique has the advantage of less blood loss, and shorter catheter time and hospital stay.
我们确定了 1318nm 二极管 Eraser 激光(奥地利萨尔茨堡的 Rolle 和 Rolle)经尿道前列腺剜除术的安全性和有效性。该激光已成功用于肺转移瘤的切除。它可以安全有效地切割和凝固富含血管的组织。我们描述了一项前瞻性、随机试验,比较了 Eraser 激光前列腺剜除术与双极经尿道前列腺切除术。
共有 60 例下尿路症状提示膀胱出口梗阻且经直肠超声提示前列腺平均大小为 59.5ml 的患者随机分为 Eraser 激光前列腺剜除术或双极经尿道前列腺切除术。患者在术前、术后 1 个月和 6 个月进行评估。
Eraser 激光前列腺剜除术在改善国际前列腺症状评分、最大尿流率和生活质量方面与双极经尿道前列腺切除术相当。激光剜除术在出血量(平均 ± SD 116.83 ± 97.02 比 409.83 ± 148.61ml)、导尿管时间(平均 32.80 ± 8.74 比 65.73 ± 13.72 小时)和住院时间(平均 45.13 ± 14.77 比 91.20 ± 11.76 小时)方面明显优于双极经尿道前列腺切除术(均为 p <0.05)。使用经过验证的 Clavien-Dindo 系统,有 3 例 ID 级和 1 例 II 级并发症。
Eraser 激光前列腺剜除术和双极经尿道前列腺切除术在缓解膀胱流出道梗阻和下尿路症状方面同样安全有效。这种激光技术具有出血少、导尿管时间和住院时间短的优点。