[结直肠癌肝转移的动脉内治疗]
[Intra-arterial treatment of liver metastases from colorectal carcinoma].
作者信息
Pellerin O, Geschwind J-F
机构信息
Faculté de médecine, université Paris Descartes, 75270 Paris cedex 06, France.
出版信息
J Radiol. 2011 Sep;92(9):835-41. doi: 10.1016/j.jradio.2011.07.008. Epub 2011 Sep 1.
Abstract
Colorectal carcinoma is a major public health concern with its yearly mondial incidence of about one million cases and yearly mortality of 500,000 cases. The liver is the organ most frequently affected by metastases with a frequency of 40 to 60% (contemporaneous in 25% of cases). While surgical resection is the only curative therapy, many patients are not such candidates due to the infiltrative nature of the liver metastases. Systemic chemotherapy and biotherapy regimens are the conventional treatment options for patients with multiple liver metastases. Under such circumstances, intra-arterial therapy may play a major role. We will review the main types of endovascular therapies for liver metastases from colorectal carcinoma including indications, results and potential complications.
摘要
结直肠癌是一个重大的公共卫生问题，其全球年发病率约为100万例，年死亡率为50万例。肝脏是最常受转移影响的器官，转移发生率为40%至60%（25%的病例为同期转移）。虽然手术切除是唯一的治愈性疗法，但由于肝转移的浸润性，许多患者并非手术候选者。全身化疗和生物治疗方案是多发肝转移患者的传统治疗选择。在这种情况下，动脉内治疗可能发挥主要作用。我们将综述结直肠癌肝转移的主要血管内治疗类型，包括适应证、疗效及潜在并发症。
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