Morris-Stiff Gareth, Ogunbiyi Samuel, Rees Jonathan, Davies Colin J, Hicks Eryl, Lewis Michael H
Department of Surgery, Royal Glamorgan Hospital, Ynysmaerdy, Llantrisant, UK.
Ann R Coll Surg Engl. 2011 May;93(4):306-9. doi: 10.1308/003588411X571999.
While large epidemiological studies have suggested that the male gender is more frequently afflicted with intermittent claudication, there is little data whether there are gender differences in the distribution of peripheral vascular disease (PVD). The aim of this study was to clarify this issue on the basis of angiographic findings in patients presenting with claudication.
The radiology department computerised database was used to identify all lower limb angiograms performed for investigation of PVD. Patients undergoing incomplete assessment and those with normal angiograms were excluded. Demographic details for each patient were collected together with details of uni- or bilaterality of disease, the number of lesions present and their anatomical distribution according to the major named vessels. Only lesions reported as radiologically significant were included in the analysis.
Five hundred consecutive angiograms fitting the defined study criteria were assessed. There were 310 males and 190 females giving a male to female ratio of 1.6:1. The most common distribution for both genders was multiple bilateral lesions. There were no significant differences in the number of stenoses in terms of ratio of bilateral to unilateral (2.39 vs 2.77) or ratio of multiple to single lesions (1.5 vs 1.7) between the female and male groups. Disease was more common in males at all anatomical locations, the most significant differences being for lesions of the common femoral and profunda femoris arteries.
PVD is more commonly diagnosed in males than females. The disease process is more commonly bilateral in both genders and PVD affects more numerous sites in the male claudicant than in the female claudicant. Nevertheless, there does not appear to be any difference in the anatomical distribution of disease between genders.
虽然大型流行病学研究表明男性更常患间歇性跛行，但关于外周血管疾病（PVD）分布是否存在性别差异的数据很少。本研究的目的是根据跛行患者的血管造影结果来阐明这一问题。
利用放射科计算机数据库识别所有为检查PVD而进行的下肢血管造影。排除评估不完整的患者和血管造影正常的患者。收集每位患者的人口统计学细节以及疾病单侧或双侧的细节、病变数量及其根据主要命名血管的解剖分布。仅将报告为具有放射学意义的病变纳入分析。
评估了连续500例符合既定研究标准的血管造影。男性310例，女性190例，男女比例为1.6:1。男女最常见的分布都是双侧多发病变。女性和男性组之间，双侧与单侧狭窄比例（2.39对2.77）或多发与单发病变比例（1.5对1.7）方面的狭窄数量没有显著差异。在所有解剖部位，疾病在男性中更常见，最显著的差异在于股总动脉和股深动脉的病变。
PVD在男性中的诊断比女性更常见。疾病过程在男女中更常见于双侧，与女性跛行患者相比，PVD在男性跛行患者中影响的部位更多。然而，两性之间疾病的解剖分布似乎没有任何差异。
