Department of Rheumatology, South Infirmary Victoria University Hospital, Cork, Ireland.
Rheumatol Int. 2013 Jan;33(1):239-40. doi: 10.1007/s00296-011-2155-9. Epub 2011 Sep 24.
Varicella is a self-limiting and relatively mild disease of childhood, although it is frequently more severe and complicated among the immunocompromised rheumatology patients on immunomodulator therapies. In addition, future reactivation of the dormant virus in dorsal root ganglia may cause herpes zoster infection, which can be very debilitating. In this manuscript, we discuss the nature of this infection along with its potential vaccine especially among rheumatology patients.
水痘是一种自限性的、相对温和的儿童疾病,但在接受免疫调节剂治疗的免疫功能低下的风湿免疫病患者中,病情往往更为严重和复杂。此外,潜伏在背根神经节中的病毒可能会再次激活,导致带状疱疹感染,这可能非常虚弱。在本文中,我们讨论了这种感染的性质及其潜在的疫苗,特别是在风湿免疫病患者中。