Palazzo L, Gayet B, Vilgrain V, Molas G, Amouyal P, Roseau G, Ponsot P, Amouyal G, Fékéte F, Paolaggi J A
Service de Gastroentérologie, Hôpital Beaujon, Clichy.
Gastroenterol Clin Biol. 1990;14(5):428-36.
To investigate whether endoscopic ultrasonography could improve the preoperative staging of esophageal carcinoma we prospectively studied 56 tumors in 51 patients between March 1987 an March 1988. The results for assessing local and regional extension and preoperative staging were compared with those of computed tomography, surgery, and pathological findings. When the procedure was complete (n = 25) the accuracy of parietal spread assessment was 85.7 percent; sensitivity for nodal involvement was 83.3 percent versus 50 percent for computed tomography with an accuracy of 97.6 percent versus 96.4 percent; the discrimination between superficial and advanced cancer was 100 percent; the accuracy for preoperative staging using the Japanese classification was 84 percent. When the procedure was not complete (stenosis), endoscopic ultrasonography was complementary to computed tomography: local invasion of anatomical structures (n = 16) was better assessed by combined endoscopic ultrasonography and computed tomography (n = 11) than by endoscopic ultrasonography (n = 8) or computed tomography (n = 6) alone. We conclude that endoscopic ultrasonography is the best procedure for staging esophageal carcinoma without stenosis; further miniaturization of the transducer is necessary to improve results in the case of narrow stenosis.
为研究内镜超声检查能否改善食管癌的术前分期,我们于1987年3月至1988年3月对51例患者的56个肿瘤进行了前瞻性研究。将评估局部和区域扩展及术前分期的结果与计算机断层扫描、手术及病理检查结果进行了比较。当检查完成时(n = 25),壁层扩散评估的准确率为85.7%;淋巴结受累的敏感性为83.3%,而计算机断层扫描为50%,准确率分别为97.6%和96.4%;浅表癌与进展期癌的鉴别率为100%;采用日本分类法进行术前分期的准确率为84%。当检查未完成(狭窄)时,内镜超声检查是计算机断层扫描的补充:联合内镜超声检查和计算机断层扫描(n = 11)对解剖结构局部侵犯的评估(n = 16)优于单独的内镜超声检查(n = 8)或计算机断层扫描(n = 6)。我们得出结论,内镜超声检查是无狭窄食管癌分期的最佳方法;为改善狭窄严重时的检查结果,换能器进一步小型化很有必要。